death
Ten years after Brexit, it seems reasonable to ask what effects Brexit has caused on health-related matters for the UK and beyond. Here is my attenpt to provide an answer; these are the 8 issues that come to my mind:
- Workforce Disruption and Recruitment Shift: The ending of free movement led to a sharp drop in EU-trained doctors, nurses, and social care staff. To plug these vacancy gaps, the UK was forced into recruiting heavily from non-EU nations. This created a fragile reliance on international recruitment from countries facing their own healthcare worker shortages. In turn, this further supported the xenophobic sentiments of some UK citizens.
- Medicine Supply Problems: Leaving the EU single market introduced significant customs and regulatory friction. This friction directly contributed to the frequency and severity of local pharmaceutical shortages in the UK.
- Loss of Regulatory Leverage: By exiting the European Medicines Agency (EMA), the UK became a standalone market. Pharmaceutical companies now regularly prioritize the much larger EU and US markets for rolling out cutting-edge new treatments, leaving the UK Medicines and Healthcare products Regulatory Agency (MHRA) to act as a “rule-taker” by fast-tracking approvals already granted elsewhere.
- Cross-Border Friction: Reciprocal healthcare arrangements became more complex under the new Global Health Insurance Card (GHIC) system. While basic travel is covered, specialized cross-border medical networks face ongoing administrative and legal hurdles. Many British ex-pats’ found themselves without health cover.
- Regulatory Divergence in Training and Innovation: The UK has increasingly diverged from EU rules, such as lowering the mandatory clinical training hours required for a nursing degree to get staff into hospitals faster. Additionally, medical technology and AI developers now face double-compliance costs (clearing separate UK and EU hurdles). This makes the UK a more expensive market to launch new health technologies.
- The Macro-economic Squeeze: The overall economic downturn resulting from Brexit reduced UK GDP, shrinking the available tax revenues. This has directly limited the government’s financial capacity to fund the NHS, to clear post-pandemic backlogs, and to invest in long-term social care reform.
- Exacerbating Health Inequalities: As inflation, food costs, and supply chain disruptions damaged the UK, vulnerable socioeconomic groups have been hit the hardest. These economic pressures, combined with a chronically strained social care sector, significantly widen UK health inequalities.
- Compounding Pressure on Patient Outcomes: While ultimate health metrics, such as mortality rates and overall life expectancy, are influenced by dozens of complex variables, an underfunded NHS, chronic staffing vulnerabilities, and restricted access to new drugs create a persistent, negative headwind against public health which, in the long run, can only negatively affect patient outcomes.
All of these effects are clearly negative.
Can anyone think of a positive effect?
I can’t!
The claim that Elon Musk might be “killing millions” sounds like hyperbolic rhetoric, but it is an entirely predictable mathematical projection of his policy choices. Peer-reviewed global health modeling showed that the systematic dismantling of USAID—spearheaded by Musk’s Department of Government Efficiency (DOGE)—will result in over 14 million preventable deaths by 2030, millions of whom are children. By freeze-framing and terminating programs that provide life-saving vaccines, malaria bed nets, and HIV therapeutics, these actions have directly triggered the resurgence of entirely controllable diseases.
Hard to believe?
See for yourself; here is the abstract of the paper published in the Lancet:
Background: Official development assistance (ODA) accounts for the majority of humanitarian and development assistance in the world’s most vulnerable countries and has played a pivotal role in advancing global health. We aimed to comprehensively evaluate the impact of ODA funding on mortality across the past two decades, and to project the potential consequences of current defunding trends.
Methods: We conducted an integrated retrospective evaluation and forecasting analysis using longitudinal panel data from 93 low-income and middle-income countries (LMICs). First, we estimated the association between ODA per-capita funding and mortality outcomes from 2002 to 2021 using a two-ways fixed-effects multivariable Poisson regression model with robust standard errors, adjusted for all relevant demographic, socioeconomic, and health-system covariates. We then assessed age-specific and cause-specific effects, performing extensive sensitivity and triangulation analyses to test the robustness and causal interpretation of results. Finally, we integrated the retrospective impact estimates into validated country-level microsimulation models to forecast mortality under three defunding scenarios up to 2030: a business-as-usual trajectory, a severe defunding scenario, and a mild defunding scenario.
Findings: Higher ODA funding levels were associated with a 23% reduction in age-standardised all-cause mortality (rate ratio [RR] 0·77; 95% CI 0·70-0·85) and a 39% reduction in under-5 mortality (0·61; 0·49-0·75). ODA funding was associated with large mortality declines in major communicable diseases: 70% for HIV/AIDS (RR 0·30; 95% CI 0·24-0·39), 56% for malaria (0·44; 0·35-0·56), 56% for nutritional deficiencies (0·44; 0·30-0·65), and 54% for neglected tropical diseases (0·46; 0·36-0·59). Significant reductions were also observed in mortality from tuberculosis, diarrhoeal diseases, lower respiratory infections, and maternal and perinatal causes. Forecasting analyses projected that ongoing reductions in ODA funding could, under a severe defunding scenario, result in 22·6 million (95% uncertainty interval [UI] 16·3-29·3) additional deaths across all ages by 2030, including 5·4 million (4·1-6·8) among children younger than 5 years. Under a mild defunding scenario-defined as a continuation of current downward trends-the projected excess deaths would be 9·4 million (95% UI 6·2-12·6) overall and 2·5 million (1·8-3·2) among children younger than 5 years.
Interpretation: ODA funding has played a decisive role in reducing preventable mortality across LMICs over the past two decades, and the abrupt withdrawal of this support threatens to cause millions of avoidable deaths, reversing decades of progress in global health.
Funding: RF Catalytic Capital and the Spanish Ministry of Science and Innovation.
Attempting to shield Musk from the moral indictment of these deaths by hiding behind bureaucratic complexity is a cop-out. Musk is not a passive advisor suggesting minor budgetary trims; he has aggressively engineered and celebrated the destruction of these aid mechanisms on his public platform, explicitly branding the defunding of life-saving infrastructure as “clipping waste.” When an individual wields unchecked power to eliminate interventions with legally and medically proven survival rates, the line between “efficiency” and institutional negligence disappears. He is fully aware of the survival benefits of these programs, making the choice to dismantle them a calculated acceptance of mass mortality.
While defenders argue that epidemiological models deal in macro-statistics rather than localized causality, this defense elides the nature of modern accountability. Musk cannot hand-select which specific child dies of malaria, but he did hand-select the budget line that funded their treatment. Pretending this is just a structural or collective government failure sanitizes the reality: a single billionaire used his leverage to treat global survival infrastructure like an unprofitable corporate acquisition, making him materially and morally responsible for the human body count that follows.
In March 2025, a federal judge ruled that DOGE’s effort to dismantle USAID likely violated the Constitution and ordered restoration of access to key systems, saying USAID had been effectively eliminated. That matters because it weakens any claim that the dismantling was merely speculative or rhetorical: courts have already treated the shutdown effort as legally serious.
For a deeper look into the systemic impact of these specific health program suspensions and the firsthand accounts of how these funding disruptions unfolded on the ground, you can watch this France 24 Interview with a USAID Whistleblower.
Internal HHS and CDC communications leaked by the US Senate HELP Committee expose a truly scary crisis of institutional integrity. Secretary Robert F. Kennedy Jr. systematically dismantled evidence-based public health infrastructure to implement his personal, ideological and dangerous agenda. This was not merely a shift in administrative policy; it was an aggressive, top-down politicisation of science that directly compromised public safety.
It is now clear that less than 24 hours after his confirmation on 29/30 January 2025 – in the midst of a severe flu season that had already claimed 16,000 lives, including 68 children – Kennedy issued a direct mandate to halt active flu vaccine public service advertisements. Internal communications from HHS Director of Communications Andrew Nixon explicitly confirm this “was a direct ask from Secretary Kennedy.”
The institutional damage caused by Kennedy’s actions extends far beyond suppressed messaging into structural purges. In fact, it seems likely that Kennedy committed perjury. During his confirmation hearings, Kennedy misled lawmakers regarding his intentions to restrict vaccine access and his past anti-vaccine interventions. Once in power, his chief of staff enforced an “absolute need for political review” over career scientists. Kennedy subsequently fired the entire 17-member Advisory Committee on Immunization Practices (ACIP), replacing them with people with strong anti-vaccine views. When career CDC Director Susan Monarez resisted rubber-stamping these politically motivated recommendations, Kennedy fired her, triggering a wave of high-level resignations among the agency’s top medical officers.
The leaked emails also confirm that Kennedy bypassed standard scientific clearance protocols to dispatch handpicked researchers into confidential CDC databases. This was a deliberate attempt to weaponize raw public health data to manufacture evidence for a spurious vaccine-autism link that has been thoroughly debunked by global longitudinal studies involving millions of children.
By substituting ideological loyalty for empirical evidence, the US administration has compromised the foundational mechanics of medicine. When a federal health agency is forced to prioritize dogma over data, the ultimate cost is inevitably paid in preventable human disease and death.
The conclusion: Kennedy has likely committed the serious crime of perjury, has shown to be a danger to our (the damage can quickly spread beyond the US) health, and in my view has to be removed from office asap.
The US Defense Secretary Pete Hegseth’s decision to make the annual flu vaccine optional for US military service members in April 2026 was not an exercise in “medical autonomy,” as he called it at the time. It was a recklessly ideological act that has now already cost a life. By lifting a long-standing, evidence-based mandate Hegseth dismissed as “absurd” and “overreaching,” he prioritized ill-advised principles over the health, welfare, and readiness of US service members.
The consequences arrived swiftly and were confirmed in mid-June 2026. At Lackland Air Force Base in Texas, at least 159–160 recruits fell ill with flu within weeks, with two hospitalizations. One sixth-week trainee, Keon McDaniel, died on June 16 at Brooke Army Medical Center after a medical emergency on June 12. While the official cause of death remains under investigation, sources report McDaniel had not received the flu vaccine. Vaccination rates among Air Force trainees plummeted to roughly 40% after the mandate was lifted, compared to near 100% coverage while immunization was mandatory.
The outbreak was so severe that the Air Force received an emergency exception from the Pentagon and reinstated mandatory flu shots for all recruits at Lackland – an admission that Hegseth’s policy was dangerously wrong. The exception was granted by the Under Secretary of Defense for Personnel and Readiness, which can authorize mandatory vaccination when risk assessments warrant it.
Hegseth styled himself “Secretary of War” while declaring mandatory vaccination “not rational.” Yet the mathematics of infectious disease are clear: in communal settings like military bases, where close contact is unavoidable, voluntary vaccination leads almost inevitably to outbreaks. Yet Hegseth ignored decades of public health evidence that flu vaccines reduce morbidity, prevent complications, and maintain operational readiness. His decision was irresponsible and little more than political posturing aligned with anti-vaccination rhetoric that currently undermines public health across the US under Trump’s administration.
The death of a young trainee is a human cost Hegseth cannot dismiss. Texas Congressman Joaquin Castro is now calling for a full DoD accounting of the outbreak and an investigation into McDaniel’s death. Whenever military leaders make policy decisions, they must prioritize readiness and safety over ideology. Hegseth failed that duty in the most appalling fashion. His flu shot reversal was by no way a victory for autonomy; it was a failure of leadership that endangered service members and will likely cost more lives if not urgently corrected across the entire armed forces.
As of June 20, 2026, the mandatory flu vaccine has not been reinstated across all armed forces – only at Lackland. The broader policy remains voluntary, leaving the rest of the military exposed to Hegseth’s stupidity and similar outbreaks.
Robert F. Kennedy Jr., the U.S. Health and Human Services secretary, is demanding that the journal Toxicology Reports explain in detail why it removed a 2021 paper he has cited in support of his anti-vaccine stance. The study had concluded that “While the findings in this paper are not proof of an association between infant vaccines and infant deaths, they are highly suggestive of a causal relationship.”
In his letter to the editors, Kennedy accuses the journal of suppressing research linking vaccines to sudden infant death. However, the evidence reveals quite clearly that Kennedy is not seeking transparency but rather attempting to bully a peer-reviewed journal that correctly identified fatal methodological flaws in a paper Kennedy continues to promote.
The removed study claimed to link vaccines to infant deaths using data from the Vaccine Adverse Event Reporting System (VAERS). The journal removed the paper because VAERS is a passive reporting system that cannot establish causality. Any conclusion claiming vaccines cause deaths from such data is therefore not valid. The editors determined the methodology was seriously flawed and that the author’s responses to critiques were unsatisfactory. Consequently, the paper would mislead readers and harm the public. In this situation, it would have been unethical NOT to retract!
Kennedy’s demand for a “full explanation” ignores that the journal had already provided a clear, evidence-based removal notice. He wants to know who reviewed the paper and what standards were applied, yet these are standard peer-review procedures. Framing a legitimate scientific correction as censorship reveals Kennedy’s disregard for science and evidence-based medicine. As HHS secretary, he is responsible for protecting public health, yet he continues to cite fraudulent research that contradicts established scientific consensus on vaccine safety.
The story is reminiscent of the ongoing conflict over the landmark Danish vaccine study published in the Annals of Internal Medicine. It tracked over 1.2 million children born in Denmark between 1997 and 2018. Exploiting a natural experiment created by evolving national immunization schedules, researchers analyzed the dose-response relationship of aluminum adjuvants. The study found no evidence linking increased cumulative exposure to an elevated risk of 50 chronic pediatric conditions, including neurodevelopmental, autoimmune, and allergic disorders.
Despite its massive scale and rigorous design, Kennedy labeled the research a “deceitful propaganda stunt” and demanded its retraction. However, Kennedy’s criticisms rely on data misrepresentation and a fundamental misunderstanding of epidemiological methodology. First, Kennedy cherry-picked non-significant supplementary data, falsely claiming a 67% increased risk of Asperger’s syndrome. In reality, the finding had a wide confidence interval, lacked statistical significance, and completely vanished when researchers analyzed the full follow-up data. Second, Kennedy objected to the lack of a completely unvaccinated control group. Experts counter that the unvaccinated cohort (1.2%) was too small to measure rare outcomes accurately and would introduce severe confounding bias due to differing family lifestyles. Finally, Kennedy levelled inaccurate claims of financial corruption against Denmark’s Statens Serum Institut, a public research body that had long since divested its vaccine manufacturing arm.
The medical community has firmly rejected Kennedy’s attacks. The journal refused his retraction demand, and independent experts have defended the study as the strongest available evidence of vaccine aluminum safety. After all, aluminum salts have been used safely for a century, and vaccine-derived amounts are eclipsed by daily environmental and dietary intake.
The inescapable conclusion is that Kennedy’s campaigns are not about accountability or about promoting scientific rigor; they are about promoting his dangerous type of misinformation. His continued advocacy of pseudoscience exposes his commitment to ideology over evidence, a truly dangerous stance for anyone leading the nation’s health agency. It is high time, I feel, that he gets sacked before he does any more lasting damage to public health in the US and beyond!
Dr. Toby Rogers, a political economist and fellow at the libertarian Brownstone Institute, ignited a firestorm in March 2026 when he declared the current childhood vaccination program “one of the greatest crimes in human history” (“libertarian” refers to someone who advocates for extreme individual liberty—particularly freedom from government mandates and regulations—believing that the state should be minimized and that individuals should have absolute autonomy over their own bodies, property, and choices without state coercion).
Rogers’ 2026 statement is not an isolated outburst but the culmination of years of vaccine skepticism. After his partner’s son was diagnosed with autism in 2015, Rogers abandoned his original doctoral focus to study autism’s causes, reviewing nearly 1,000 studies over four years. He concluded that vaccines are the primary driver of the autism epidemic. The overwhelming scientific consensus, however, is that vaccines are safe and that autism’s rise stems from improved diagnosis, broader criteria, and complex genetic and environmental factors unrelated to immunization (see the plethora of previous posts on this subject). His PhD thesis, The Political Economy of Autism, and subsequent publications have been widely criticized by the scientific community. Its methodological flaws include:
- selection bias,
- cherry-picking,
- inclusion of weak studies,
- dismissing robust epidemiological research.
Rogers’ 2026 statement elevates personal conviction and contested research over scientific rigor and public health reality. Rogers argues that children receive too many vaccines too early, warning of “cumulative effects” on developing immune systems. Yet the Institute of Medicine has found no evidence of major safety concerns with the current childhood immunization schedule, and the National Academy of Sciences has repeatedly affirmed that vaccines are safe and effective. Rogers dismisses the 22 major studies confirming vaccine safety as “worthless” because they lacked a true unvaccinated control group—a standard that is both ethically impossible and scientifically unnecessary given the massive population data demonstrating vaccine safety over decades.
Rogers’ evidence relies heavily on a handful of independent studies to support his claims. These studies have been criticized for small sample sizes, selection bias, failure to control for confounders, and methodological flaws so severe that some of Rogers’ co-authored papers, such as “Autism Tsunami,” were retracted from peer-reviewed journals. His claim that vaccinated children have dramatically higher rates of autism and chronic disease rests on research that has not withstood independent replication or scrutiny by mainstream scientists. By contrast, the scientific community’s confidence in vaccine safety derives from massive, longitudinal studies involving millions of children, rigorous clinical trials, and decades of population surveillance.
Rogers’ credibility is compromised not least because he is a regular contributor to Children’s Health Defense, an anti-vaccine organization founded by Robert F. Kennedy Jr. that has a long history of spreading debunked claims. Roger’s testimony before the US Senate Subcommittee on Investigations in September 2025, titled “How the Corruption of Science has Impacted Public Perception and Policies Regarding Vaccines,” tried to position him as a whistleblower exposing “flawed science.” In reality, it relied on the same flawed studies and conspiracy narratives that have been repeatedly discredited by the scientific community.
Rogers receives funding from several anti-vaccine and libertarian organizations, though specific salary figures are not publicly disclosed :
- Brownstone Institute is a libertarian think tank founded by economist Jeffrey Tucker that promotes vaccine skepticism, “medical freedom,” and opposition to public health mandates. The institute is funded by libertarian donors and provides fellowships to researchers who align with its ideology.
- Children’s Health Defense is explicitly an anti-vaccine organization led by Mary Holland (CEO) and founded by Robert F. Kennedy Jr. The organization has illuminated funding sources through IRS 990 filings, showing it raised millions of dollars and pays researchers, speakers, and staff. In Rogers’ Senate testimony, he explicitly stated: “Since then I’ve continued my research with Children’s Health Defense, as an independent journalist, and as a Fellow at Brownstone Institute”.
- Rogers also appears at MAHA Institute conferences (Make America Healthy Again), which is aligned with HHS Secretary Robert F. Kennedy Jr.’s movement and features speakers from anti-vaccine organizations including Children’s Health Defense.
Rogers’s financial ties to anti-vaccine organizations create clear conflicts of interest. His research supports the organizational mission of Children’s Health Defense and Brownstone Institute, and his income appears tied to producing content that aligns with these organizations’ anti-vaccine advocacy. The political economy of Rogers’ work is thus ironic: while he critiques the “political economy of autism” and government response, his own research is funded by private organizations with clear ideological and financial incentives to promote vaccine skepticism.
Rogers is not a medical doctor. He has a doctorate in political economy from the University of Sydney and a Master’s in public policy. He holds no medical degree or formal training in medicine, immunology, epidemiology, or vaccine science. His expertise is in political economy, not medical or vaccine research, which means his claims about vaccine safety and autism lack the scientific credentials required to make authoritative medical assertions.
Smoking kills! Since most people now know about this fact, they have been looking for alternatives that are safe. Here I will discuss two of them: vaping and nicotine pouches.
VAPING
Vaping devices are electronic nicotine delivery systems that heat liquid into an inhalable aerosol. They have surged in popularity. Despite marketing claims to the contrary, substantial evidence reveals significant health risks.
Addiction
Nicotine, the primary active ingredient in most vape liquids, is one of the most addictive substances known. Research indicates that 17.8% of e-cigarette users report feeling “very addicted,” while 42.3% consider e-cigarettes equally or more addictive than combustible cigarettes. The addictive potential is amplified by several factors: modern vape devices use nicotine salts that deliver nicotine more rapidly and in higher concentrations than traditional cigarettes, and the high nicotine concentrations in many devices (often not listed on packaging) accelerate dependence. The more a person vapes, the more their brain and body adapt to nicotine, making cessation increasingly difficult. When nicotine enters the system, it triggers dopamine release, creating a “feel-good” sensation that reinforces continued use. However, nicotine’s effects wear off rapidly, triggering cravings and establishing a cycle of dependence. Nearly all vapes circulating contain nicotine, even when not listed on packaging, making prevaping users unknowingly vulnerable to addiction.
Toxicity
Vaping exposes users to a complex toxic chemical cocktail. The e-liquids contain propylene glycol and vegetable glycerin. These are ingredients meant to be eaten, not inhaled which become toxic when heated. When vaporized, these components transform into dangerous chemicals including acetaldehyde, acrolein, and formaldehyde, all of which can cause lung disease and cardiovascular disease. The two primary e-cigarette ingredients in the US are toxic to cells, with toxicity increasing alongside the number of additives in the e-liquid. Acrolein, a herbicide primarily used to kill weeds present in e-cigarettes, can cause acute lung injury, COPD, asthma, and potentially lung cancer. Vitamin E acetate, a thickening agent sometimes added to THC-containing vape products, was identified by the CDC as a “chemical of concern” in vaping-associated lung injuries. Flavoring agents pose additional risks. Diacetyl, a flavoring chemical linked to “popcorn lung” (bronchiolitis obliterans), is present in many flavored vapes and causes irreversible lung damage. Secondhand emissions contain nicotine, ultrafine particles, volatile organic compounds like benzene usually found in car exhaust, and heavy metals including nickel, tin, and lead. The FDA has not found any e-cigarette to be safe and effective for smoking cessation.
Cardiovascular disease
Vaping is associated with significant cardiovascular risks. Research has linked nicotine-containing e-cigarettes to acute changes in blood flow, including increased blood pressure and heart rate. These physiological effects can lead to atherosclerosis and increase the risk of heart attacks and strokes. Other e-cigarette ingredients, particularly flavoring agents, independently carry risks associated with heart and lung diseases in animal studies. A recent analysis found a significant association between former or current e-cigarette users and the development of several respiratory diseases within two years of use, suggesting cardiovascular and respiratory systems are simultaneously compromised.
Brain damage
The human brain does not fully develop until approximately age 25, making young users uniquely vulnerable. Regular nicotine vape use causes changes to brain development that negatively affect learning, concentration, mood, and memory. Nicotine rewires the brain, changing the parts responsible for decision-making, impulse control, and mood regulation. These changes can interfere with mood and make users more likely to become addicted to nicotine and other drugs. Nicotine exposure during adolescence also increases feelings of stress and worsens depression and anxiety. Vaping hasn’t been around long enough to see irreversible diseases yet, but biologically, damage is happening and inflammation is occurring—creating conditions that will lead to diseases later.
References
- American Lung Association. (n.d.). Health Risks of E-Cigarettes and Vaping. https://www.lung.org/quit-smoking/e-cigarettes-vaping/impact-of-e-cigarettes-on-lung
- American Lung Association. (2025). The Truth About What Vaping Is Doing to Your Body. https://www.lung.org/blog/illnesses-vaping-causes
- Panagis Galiatsatos, M.D., MHS. Johns Hopkins School of Medicine.
- European Journal of Public Health. (2022). Understanding addiction in e-cigarette users – the EVAPE project. Oxford Academic. https://academic.oup.com/eurpub/article/32/Supplement_3/ckac130.078/6765989
- National Institutes of Health. (2024). The Risks of Vaping. NIH News in Health. https://newsinhealth.nih.gov/2020/05/risks-vaping
- American Heart Association. (2023). As E-Cigarette Use Grows, More Research Needed on Long-Term Effects of Vaping. https://www.stroke.org/en/news/2023/07/17/as-e-cigarette-use-grows-more-research-needed-on-long-term-effects-of-vaping
- NSW Health. (n.d.). Vaping – Nicotine Addiction | Young People Factsheet. https://www.health.nsw.gov.au/tobacco/Factsheets/vaping-nicotine-addiction-young-people-factsheet.pdf
- Centers for Disease Control and Prevention. (2025). Health Effects of Vaping. https://www.cdc.gov/tobacco/e-cigarettes/health-effects.html
- National Institutes of Health. (2025). NIH-Funded Studies Show Damaging Effects of Vaping, Smoking on Blood Vessels. https://www.nih.gov/news-events/news-releases/nih-funded-studies-show-damaging-effects-vaping-smoking-blood-vessels
- Johns Hopkins Medicine. (2025). 5 Vaping Facts You Need to Know. https://www.hopkinsmedicine.org/health/wellness-and-prevention/5-truths-you-need-to-know-about-vaping
NICOTINE POUCHES
Nicotine pouches are small, smokeless, tobacco-free pouches containing nicotine. They have existed for a long time but have recently rapidly gained popularity, particularly among young people. They are often claimed to be safer alternatives to cigarettes. Is this claim true?
Addiction
Nicotine pouches are highly addictive by design. Nicotine is a well-established addictive drug that activates reward pathways in the brain, leading to dependence. Research demonstrates that nicotine salts used in pouches deliver higher concentrations more rapidly than traditional nicotine products, accelerating addiction. Among young people who try nicotine pouches, 73% continue using them, indicating strong addictive potential. The average user consumes half a can daily (8-12 pouches), with 10 pouches at 6mg equivalent to 1–1½ packs of cigarettes or 1½ e-cigarette pods daily. Alarmingly, the number of youths using nicotine pouches has doubled in the US since 2021, reaching now ~400,000 users. This rapid uptake among youth suggests that the product’s smokeless, odorless features make nicotine use more accessible and socially acceptable, facilitating addiction before users fully understand the consequences.
Toxicity
Nicotine pouches contain unregulated and potentially toxic levels of nicotine. While nicotine itself is not unregulated, many products in the US lack FDA authorization and are on the market illegally without proper safety testing. A 2022 study found that 26 of 44 nicotine pouch products contained cancer-causing chemicals, including ammonia, formaldehyde, chromium, and nickel. These contaminants likely result from inadequate manufacturing processes and quality control. The absence of standardized regulation means nicotine concentrations can vary significantly between products and even within batches, making dosing unpredictable. Furthermore, non-tobacco nicotine products may seem healthier than smoking, but they come with their own laundry list of health effects, and public health experts recommend avoiding nicotine altogether.
Cardiovascular disease
The cardiovascular risks associated with nicotine pouches are well-documented. Nicotine increases blood pressure, heart rate, and blood flow to the heart while constricting arteries. These physiological effects can lead to atherosclerosis and heart attacks. The American Heart Association explicitly warns that nicotine can damage the heart and other vital organs. However, some industry-sponsored research claims that nicotine administered through pouches has only transient effects on blood pressure and heart rate in healthy users, with no demonstrated long-term cardiovascular damage. This discrepancy highlights the importance of independent research versus industry-funded studies. Nevertheless, the mechanistic evidence—nicotine’s vasoconstrictive and hemodynamic effects—strongly suggests increased cardiovascular risk, particularly with chronic use or in individuals with pre-existing conditions.
Brain dmage
Nicotine damages brain development. The human brain does not fully develop until approximately age 25, making adolescents and young adults uniquely vulnerable to nicotine’s neurotoxic effects. Nicotine exposure during adolescence alters the development of the prefrontal cortex, the brain region responsible for attention, learning, memory, and impulse control. These changes can be permanent, leading to lasting cognitive deficits and difficulties with concentration and memory. Additionally, adolescent nicotine exposure increases the risk of psychiatric disorders, including anxiety and depression, and priming the brain for addiction to other substances. Nicotine pouches are particularly dangerous for youth precisely because of these developmental vulnerabilities. Given that 400,000 US youths now use nicotine pouches, the public health implications are substantial.
References
- American Lung Association. (2024). ZYN 101: What to Know About Big Tobacco’s Latest Addiction. https://www.lung.org/blog/zyn-nicotine-addiction
- American Heart Association. (2025). Triple Threat: The Hidden Dangers of E-Cigarettes, Oral Nicotine Pouches, and Vaping. https://www.heart.org/en/healthy-living/healthy-lifestyle/quit-smoking-tobacco/triple-threat-e-cigarettes-oral-nicotine-pouches
- Cleveland Clinic. (2024). Are Nicotine Pouches Safe? Health.ClevelandClinic.org. https://health.clevelandclinic.org/are-nicotine-pouches-safe
- Dentalcare.com. (2025). Nicotine Impact on Adolescent Brain Development. CE693. https://www.dentalcare.com/en-us/ce-courses/ce693/nicotine-impact-on-adolescent-brain-development
- Verywell Health. (2024). Is Zyn Bad for Your Heart? https://www.verywellhealth.com/is-zyn-bad-for-your-heart-8735079
- Yale Medicine. (2024). What Parents Should Know About Nicotine Pouches. https://www.yalemedicine.org/news/nicotine-pouches
- initiative to Undo. (2024). The Effects of Nicotine on the Adolescent Brain. https://www.undo.org/addicting-kids/the-effects-of-nicotine-on-the-adolescent-brain
- Tobacco Free Coalition. (2025). Not Your Grandparent’s Tobacco: The New Nicotine Products. https://www.tobaccofreeco.org/the-new-nicotine-products-2/
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Having lost several friends to lung cancer, I am convinced that the best alternative to smoking is quitting.
During outbreaks of Ebola Virus Disease (EVD), public health organizations like the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) combat “infodemics”, i.e. surges of false information and unproven so-called alternative medicine (SCAM) polluting social media (Bedrosian et al., 2016; Fung et al., 2016; Obol & Nzedibe, 2024). Because these SCAMs are ineffective and frequently dangerous, authorities issue warnings against their use. Here are just a few of the many claims that can be found:
- Bathing in or drinking hot, highly saturated saltwater solutions can sweat out or kill the Ebola virus (Fung et al., 2016). Public health agencies strongly advise against this practice. It does nothing to prevent or treat EVD and can cause severe illness and death from acute hypernatremia (Vijaykumar et al., 2019).
- Solutions containing silver nanoparticles act as powerful natural antimicrobials capable of neutralizing the Ebola virus inside the body (Fung et al., 2016). The WHO has explicitly stated that Nano Silver is an unproven compound with no demonstrated efficacy against Ebola. Authorities recommend avoiding these products, as silver accumulation can cause irreversible organ damage and a condition called argyria (which permanently turns the skin blue/gray).
- Consuming large quantities of specific botanical items, such as raw onions, ginger, or alligator peppers, can stave off infection (Nsoesie & Oladeji, 2020). These “natural cures” possess no therapeutic effects capable of stopping viral replication of the filovirus family. Relying on them creates a false sense of security, which delays life-saving, evidence-based triage and supportive care (Fridman et al., 2025; Nsoesie & Oladeji, 2020).
- Ebola has been attributed to spiritual curses or witchcraft that can only be reversed by traditional spiritual cleansing (Bedrosian et al., 2016). Public health organizations work alongside local communities to pivot away from these practices. Delaying medical intervention to seek traditional spiritual healing drastically increases community transmission and prevents patients from receiving SOTA antiviral therapies and fluid replacement, lowering survival rates (Obol & Nzedibe, 2024).
- A homeopath market “e-remedies” online, claiming that the “energy signature” of a remedy could be digitized into an audio file (Moffitt, 2018). He claimed that listening to a specific, hissing MP3 file could stimulate the body’s immune system to fight off Ebola. This prompted an investigation by the Medical Board of California into the doctor’s license for promoting unscientific and unproven online remedies (Moffitt, 2018).
- Some chiropractors claim that spinal manipulations can prevent Ebola infections, because misalignments interfere with the nervous system. Since the nervous system coordinates the immune responses, these misalignments weaken the body’s ability to recognize and destroy the Ebola virus (Terry Chiropractic Boulder). People “have nothing to fear but fear itself” regarding outbreaks if they keep their spines properly aligned to maximize their natural innate immunity. Global public health authorities and mainstream scientific institutions strongly reject these claims. There is zero credible scientific evidence demonstrating that manual spinal manipulation enhances immune competence or protects an individual against Ebola (Côté et al., 2020).
Ebola infection requires immediate, professional medical treatment. Treatments include monoclonal antibody therapeutics along with intensive supportive care. Relying on internet remedies significantly delays proper clinical treatment and increases the risk of mortality.
References
Bedrosian, S. R., Young, E. C., Smith, L. A., Cox, J. D., Manning, C., Pechta, L., Telfer, J. L., Gaines-McCollom, M., Harben, Kathy, Holmes, Wendy, Lubell, K. M., McQuiston, J. H., Nordlund, Kristen, O’Connor, John, Reynolds, B. S., Schindelar, J. A., Shelley, Gene, & Daniel, K. L. (2016). Lessons of Risk Communication and Health Promotion — West Africa and United States. MMWR Supplements, 65(3), 68–74. https://doi.org/10.15585/mmwr.su6503a10
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The death of Kristian Trend, a forty-year-old spiritual wellness coach who collapsed and died following a “Kambo” cleansing ritual in Leicester, serves as a sobering cautionary tale about the extremes of the modern alternative health movement. Having overcome a severe battle with cancer in his twenties, Trend dedicated his life to holistic wellness, meditation, and nutrition, documenting his journey under the moniker “Kristian The Feel Good Guy.”
Kambo, a waxy substance secreted by the giant leaf frog of the Amazon basin, has traditionally been utilized by indigenous tribes for its intense physiological properties. Its translation into Western “detox” circles strips away its cultural context, replacing it with pseudoscientific promises of physical rejuvenation and mental clarity. The actual ceremony is an agonizing physical ordeal: participants consume massive quantities of water before facilitators inflict superficial burns on their skin, applying the frog toxin directly to the open wounds. This practice triggers a violent systemic shock characterized by soaring heart rates, dramatic blood pressure fluctuations, severe vomiting, and acute diarrhea. Though proponents mistake this intense physical trauma for a purgative cleansing process, medical experts confirm there is no empirical evidence supporting these purported benefits.
In reality, the toll of Kambo can be lethal. Over the past decade, the substance has been increasingly linked to severe health crises, including liver failure, acute heart attacks, and sudden death. This compounding medical evidence has led nations like Australia, Brazil, and Chile to implement strict bans on the substance. Trend’s death is believed to mark the first documented Kambo fatality in the UK.
In the wake of this tragedy, Trend’s mother, Angie, has channelled her grief into calling for an immediate UK ban on Kambo to prevent further loss of life. Her public appeal emphasizes the vulnerability of individuals who, like her son, fall victim of pseudoscience and seek deeper spiritual connection and bodily purity, yet find themselves exposed to unregulated, highly toxic substances under the guise of “self-care.”
Exactly ninety-three years ago, on May 10, 1933, Nazi Germany staged one of its earliest and most symbolic assaults on intellectual freedom. Presented as a spontaneous outburst of student zeal, the book burnings were in fact a carefully orchestrated campaign to “purify” German culture and bring it into line with National Socialist ideology.
The initiative was led by the Deutsche Studentenschaft (DSt), the German Student Union, which by May 1933 had fallen firmly under Nazi control. The ideological direction and media amplification came from Joseph Goebbels’ Ministry of Public Enlightenment and Propaganda. At the Berlin bonfire, Goebbels proclaimed that “the era of extreme Jewish intellectualism is now at an end,” framing the event as a cultural turning point.
Operationally, the campaign was coordinated by the DSt’s Main Office for Press and Propaganda, under student leader Hans Karl Leistritz (often misattributed in some accounts), while members of the SA and SS ensured order and visibility at the rallies. What unfolded was not a single evening of spectacle but the culmination of a structured four-week programme titled the “Action against the Un-German Spirit.”
The campaign began on April 12 with the publication of twelve theses—deliberately echoing Martin Luther, denouncing “Jewish intellectualism” and calling for a racially defined German literature. Central to the effort were blacklists compiled by librarian Wolfgang Herrmann, identifying works deemed “un-German,” including those classified as “asphalt literature,” a derogatory term for modern, urban, and socially critical writing.
During the burnings, students ritualised the destruction by reciting “fire oaths” (Feuersprüche), each tailored to the author being condemned. When works by Sigmund Freud were thrown into the flames, for example, they denounced the “overvaluation of sexual life,” illustrating how ideological messaging accompanied the physical annihilation of texts.
The targets spanned a wide intellectual spectrum, uniting literary, scientific, and political figures under the label of cultural subversion. Among them were Erich Maria Remarque, condemned for his pacifism; Karl Marx and Rosa Luxemburg, for their political thought; and writers such as Heinrich Mann, Bertolt Brecht, Kurt Tucholsky, Alfred Döblin, and Stefan Zweig, whose works challenged nationalism or authoritarianism. Even figures like Albert Einstein and Sigmund Freud were attacked as representatives of “Jewish science,” while international authors such as Ernest Hemingway and Jack London were included for their perceived ideological nonconformity. The inclusion of Helen Keller, whose social justice writings provoked particular hostility, underscored the breadth and arbitrariness of the purge.
The international response was immediate and forceful. In New York City, more than 100,000 people demonstrated against what was widely described as the “death of the mind,” while organisations such as the American Jewish Congress organised protests and boycotts. In exile, German intellectuals sought to preserve what had been destroyed: in 1934, the Deutsche Freiheitsbibliothek in Paris began collecting copies of banned works to ensure their survival.
The events of May 10 quickly assumed a grim symbolic significance. Heinrich Heine’s earlier warning – “Where they burn books, they will ultimately burn people” – proved to be less a metaphor than a prophecy, foreshadowing the far greater crimes that would follow.