MD, PhD, MAE, FMedSci, FRSB, FRCP, FRCPEd.

education

This randomised, double blind controlled trial compared the efficacy of curcumin versus omeprazole in improving patient reported outcomes in people with dyspepsia.

The interventions were:

  • curcumin alone (C),
  • omeprazole alone (O),
  • curcumin plus omeprazole (C+O).

Patients in the combination group received two capsules of 250 mg curcumin, four times daily, and one capsule of 20 mg omeprazole once daily for 28 days.

Main outcome measure was unctional dyspepsia symptoms on days 28 and 56, assessed using the Severity of Dyspepsia Assessment (SODA) score. Secondary outcomes were the occurrence of adverse events and serious adverse events.

A total of 206 patients were enrolled in the study and randomly assigned to one of the three groups; 151 patients completed the study. Demographic data (age 49.7±11.9 years; women 73.4%), clinical characteristics and baseline dyspepsia scores were comparable between the three groups. Significant improvements were observed in SODA scores on day 28 in the pain (−4.83, –5.46 and −6.22), non-pain (−2.22, –2.32 and −2.31) and satisfaction (0.39, 0.79 and 0.60) categories for the C+O, C, and O groups, respectively. These improvements were enhanced on day 56 in the pain (−7.19, –8.07 and −8.85), non-pain (−4.09, –4.12 and −3.71) and satisfaction (0.78, 1.07, and 0.81) categories in the C+O, C, and O groups, respectively. No significant differences were observed among the three groups and no serious adverse events occurred.

The authors concluded that curcumin and omeprazole had comparable efficacy for functional dyspepsia with no obvious synergistic effect.

This study, which was funded by the Thai Traditional and Alternative Medicine Fund, has been picked up by the press and is being lauded as a solid proof of efficacy. Its authors too are not half proud of their splendid trial:

This multicentre randomised controlled trial provides highly reliable evidence for the treatment of functional dyspepsia. PPIs, widely used and approved for over-the-counter use, were compared with curcumin, a popular herbal remedy. The study design, including double blind randomisation, minimised biases. Participants met strict criteria, underwent endoscopy and were tested for H pylori infection. Furthermore, we implemented measures to minimise biases by ensuring that the individuals administering the drugs, participants receiving the drugs and individuals conducting the assessment remained blinded to the type of medications administered to the participants. The trial was carried out in hospitals, and certified individuals used standardised questionnaires for assessments. Statistical methods were appropriate and followed accepted principles.

Two follow-up appointments were scheduled, and blood tests showed no abnormal symptoms or liver function abnormalities. However, participants with high body mass index indicated a trend towards liver function impairment in the curcumin group, suggesting the need for larger studies. Some participants did not provide follow-up information, which is a study weakness. However, the number of participants who provided this information was sufficient for statistical analysis and the majority of the participants attended the follow-up visit. Therefore, it can be deduced from the results that even if the number of participants followed after drug administration increased, the study findings would not be significantly different. Another limitation of this study was the absence of long term follow-up data for all patients after treatment. This is a question that will require further investigation.

The strength of the study lies in its relevance to daily clinical practice, providing additional drug options in addition to PPIs alone, without added side effects. The study was unbiased, partially funded by government organisations and the first well designed trial comparing curcumin with PPI for functional dyspepsia, with confirmation through endoscopy and ruling out H pylori infection. Limitations of this study included the small number of patients who were lost to follow-up and the lack of long term follow-up data.

However, I am far less impressed.

Why?

Curcumin is bright yellow and has a very distinct taste/smell. Even though curumin was given in capsules, patients can easily tell what they are taking. I therefore doubt that they were adequately blinded. In fact, the authors seem to agree when they state the following:

We observed that despite improvements in pain and non-pain scores, there was no significant improvement in the SODA satisfaction scores in the O and C+O groups (table 3). A possible explanation for this observation could be related to the taste and/or smell of curcumin, which might have caused reduced pleasantness for the participants while ingesting it. This potential discomfort could offset the improvements in pain and non-pain symptoms, leading to the non-significant change in satisfaction score. Further studies may be needed to explore this hypothesis as well as to improve the palatability of curcumin.

Sadly, the success of blinding (which under such circumstances should always be tested) was not reported and probably not even quantified. If many patients were de-blinded, it seems inevitable that their expectation influenced the results. In other words, the much-lauded effect of curcumin might just be due to placebo and curcumin might be entirely useless. Or, to put it bluntly, the trial was not nearly as good as many made it out to be.

PS

Sad to see that the reviewers of a reputable journal failed to pick up on this significant flaw.

Swedish researchers examined the relationship between cognitive ability and prompt COVID-19 vaccination using individual-level data on more than 700,000 individuals in Sweden.

The analyses were based on individual-level data from several administrative registers in Sweden. The study population consisted of all men and women who enlisted for military service in Sweden between 1979 and 1997. During this period, enlistment was mandatory for men the year they turned 18 or 19. Women could not enlist for military service before 1980 but were then allowed to do so on a voluntary basis.

The study population thus covered almost the entire population of Swedish men born between 1962 and 1979, in total 750,381, as well as the sample of women who enlisted during the period of 1980–1997, in total 2703. In addressing the role of confounders, the researchers analyzed the sub-sample of 6750 twin brothers (3375 twin-pairs) in the enlistment records (identified by shared biological mother and year and month of birth).

The results show a strong positive association between cognitive ability and swift vaccination, which remained even after controlling for confounding variables with a twin-design. Consistent with this, the researchers showed that simplifying the vaccination decision through pre-booked vaccination appointments alleviates almost all of the inequality in vaccination behavior.

The authors concluded that the complexity of the vaccination decision may make it difficult for individuals with lower cognitive abilities to understand the benefits of vaccination.

On this blog, we have repeatedly discussed similar or related findings, e.g.:

I know, it would be politically incorrect, unkind, unhelpful, etc. but is anyone not tempted to simplify the issue by assuming that people who are against (COVID) vaccinations are intellectually challenged?

The American Chiropractic Association Council on Chiropractic Pediatrics (CCP) announced a new diplomate education program focused on pediatric care. The program will include 300 hours of education covering topics such as pediatric development from birth to age 16, adjusting techniques, working diagnosis, clinical application, integrated care and more…

Development of the diplomate education program has been in the works for several years, with contributions from many members of the CCP, including council president Jennifer Brocker, DC, DICCP. At the helm of course development for this education program are Mary Beth Minser, DC, CACCP, and Kris Tohtz, DC, LAc, educational coordinators for CCP. They agreed that the goal of the new program is to provide education that furthers knowledge of chiropractic pediatrics in an evidence-based, integrative way. “We wanted to make sure that we had something that aligned with ACA’s core principles,” Dr. Tohtz said. “Chiropractic-forward, yes, but scientifically focused.”

Dr. Brocker added, “There was a need for more evidence-informed education [in pediatrics]. I felt like the Council was well positioned to take this on because we had the opportunity to build it from scratch, making it what students and practicing doctors need.” …

Drs. Minser and Tohtz are excited that the diplomate program will also include a research component. “There is some lacking information when it comes to pediatric chiropractic,” Dr. Minser explained. She recently participated in the COURSE Study, an international study seeking to fill knowledge gaps in research relating to pediatric chiropractic treatment. “It was a very easy project to do, and pretty exciting to be involved,” she said. “But you have to know how to treat pediatric patients in order to be involved in those research projects. We want doctors and students [in this program] to be able to go through a case study, to be able to extract information for their clinical application from that case study or from research, or, if they would like, to write up case studies so we can get more published.”

“We feel we could really push pediatric chiropractic to a whole new level having doctors that have this type of knowledge base,” Dr. Minser said. “We just want to be the best pediatric chiropractors that we can be, and this diplomate [education] program helps [us] do that.”

____________________________________

“There is some lacking information when it comes to pediatric chiropractic.”

Really?

I think the evidence is quite clear: chiropractic has nothing to offer for ill children that other, properly trained healthcare professionals would not do better.

“We feel we could really push pediatric chiropractic to a whole new level.”

Why?

“We just want to be the best pediatric chiropractors that we can be.”

In this case, please study the evidence and you will inevitably arrive at the following conclusion:

THE BEST A CHIROPRACTOR CAN DO FOR A SICK CHILD IS TO REFER IT TO A COMPETENT DOCTOR  – A DOCTOR OF MEDICINE, NOT CHIROPRACTIC!

 

The ‘ALTERNATIVE MEDICINE HALL OF FAME’ is my creation amd is meant to honour reserchers who have dedicated much of their professional career to investigating a form of so-called alternative medicine (SCAM) without ever publishing negative conclusions about it. Obviously, if anyone studies any therapy, he/she will occasionally produce a negative finding. This would be the case, even if he/she tests an effective treatment. However, if the treatment in question comes from the realm of SCAM, one would expect negative results fairly regularly. No therapy works well under all conditions, and to the best of my knowledge, no SCAM is a panacea!

This is why researchers who defy this inevitability must be remarkable. If someone tests a treatment that is at best dubious and at worst bogus, we are bound to see some studies that are not positive. He/she would thus have a high or norma ‘TRUSTWORTHINESS INDEX‘ (another creation of mine which, I think, is fairly self-explanatory). Conversely, any researcher who does manage to publish nothing but positive results of a SCAM is bound to have a very low ‘TRUSTWORTHINESS INDEX‘. In other words, these people are special, so much so that  I decided to honour such ‘geniuses’ by admitting them to my ALTERNATIVE MEDICINE OF FAME.

So far, this elite group of people comprises the following individuals:

  1. Tery Oleson (acupressure , US)
  2. Jorge Vas (acupuncture, Spain)
  3. Wane Jonas (homeopathy, US)
  4. Harald Walach (various SCAMs, Germany)
  5. Andreas Michalsen ( various SCAMs, Germany)
  6. Jennifer Jacobs (homeopath, US)
  7. Jenise Pellow (homeopath, South Africa)
  8. Adrian White (acupuncturist, UK)
  9. Michael Frass (homeopath, Austria)
  10. Jens Behnke (research officer, Germany)
  11. John Weeks (editor of JCAM, US)
  12. Deepak Chopra (entrepreneur, US)
  13. Cheryl Hawk (chiropractor, US)
  14. David Peters (osteopathy, homeopathy, UK)
  15. Nicola Robinson (TCM, UK)
  16. Peter Fisher (homeopathy, UK)
  17. Simon Mills (herbal medicine, UK)
  18. Gustav Dobos (various SCAMs, Germany)
  19. Claudia Witt (homeopathy, Germany/Switzerland)
  20. George Lewith (acupuncture, UK)
  21. John Licciardone (osteopathy, US)

Today, it is my great pleasure to admit another osteopath to the HALL OF FAME:

Helge Franke

Helge is a German Heilpraktiker and Osteopath. On his website, he lists his publications (kindly saving me the effort of doing a Medline search):

  1. Osteopathic manipulative treatment for nonspecific low back pain: a systematic review and meta-analysis. BMC Muskuloskeletal Disorders, 2014
  2. Effectiveness of osteopathc manipulative therapy for managing symptoms of irritable bowel syndrome: a systematic review. Journal of the American Osteopathic Association, 2014
  3. Why reservations remain: A critical reflection about the systematic review and meta-analysis “Osteopathic manipulative treatment for low back pain” by Licciardone et al. Journal of Bodywork & Movement Therapies, 2012, Elsevier
  4. Osteopathic Manipulative Treatment (OMT) for Lower Urinary Tract Symptoms (LUTS) in Women. A Systematic Review and Meta-analyses. Journal of Bodywork & Movement Therapies, 2012, Elsevier
  5. Comment: Is a postural-structural-biomechanical model, within manual therapy, viable? A JBMT debate. Journal of Bodywork & Movement Therapies (2011) 15, 259-261, Elsevier
  6. Die manuelle Behandlung des Kniegelenks – veraltetes Verfahren oder alternative Option? Naturheilpraxis mit Naturmedizin 9-2010, 1019-1026, Pflaum Verlag
  7. CRPS und Osteopathie – Grenzen und Möglichkeiten DO – Deutsche Zeitschrift für Osteopathie 3-2010, 6-8, Hippokrates Verlag
  8. Research and osteopathy: An interview with Dr Gary Fryer by Journal of Bodywork & Movement Therapies. 14, 304-308, Elsevier
  9. „…there is not much we can say without any doubt“ DO Life about Gary Fryer DO – Deutsche Zeitschrift für Osteopathie 1-2010, 4-5, Hippokrates Verlag
  10. Fred Mitchell und die Entwicklung der Muskel-Energie-Techniken DO – Deutsche Zeitschrift für Osteopathie 2-2009, 4-5, Hippokrates Verlag
  11. A randomized trial of arthroscopic surgery for osteoarthritis of the knee. Commentary Forschende Komplementärmedizin 2008 Dec 15(6), 354-5, Karger
  12. Evidence-informed management of chronic low back pain with spinal manipulation and mobilization. Commentary Forschende Komplementärmedizin 2008 Dec 15(6), 353-4, Karger
  13. Interview mit Prof. Eyal Lederman Teil 1 Osteopathische Medizin, 2/2007, S.15-21, Elsevier
  14. Interview mit Prof. Eyal Lederman Teil 2 Osteopathische Medizin, 3/2007, S.22-27, Elsevier
  15. Artikel über das 3. Internationale Symposium über die Fortschritte in der osteopathischen Forschung. Osteopathische Medizin, 1-2007, S.23-24, Elsevier
  16. Die richtige Haltung des Behandlers Osteopathische Medizin, 4-2006, S.8-10, Elsevier
  17. Interview mit Laurie Hartman Osteopathische Medizin, 4-2006, S. 11-16, Elsevier
  18. Herausgeber des Sonderheftes „Functional Technique” Osteopathische Medizin, 2-2006, Elsevier
  19. Harold Hoover, Charles Bowles, William Johnston und die Geschichte der Funktionellen Technik Osteopathische Medizin, 2-2006, S.4-12, Elsevier
  20. Interview mit Harry Friedman Osteopathische Medizin, 2-2006, S.25-30, Elsevier
  21. Funktionelle Technik – Praxis Osteopathische Medizin, 2-2006, S.17-23, Elsevier
  22. Osteopathische Diagnose und Behandlung des Hüftgelenks Naturheilpraxis mit Naturmedizin, 10-2006, S.1383-1393, Pflaum-Verlag
  23. Bericht über das 2-Tage Seminar von Prof. Laurie Hartman in München Naturheilpraxis mit Naturmedizin, 5-2006, S.754-755, Pflaum Verlag
  24. Bewusstsein für Bewegung. Die minimale Hebeltechnik und das Behandlungskonzept von Laurie Hartman Osteopathische Medizin, 4-2006, S.4-7, Elsevier
  25. ICAOR 6 / Interview mit Florian Schwerla Osteopathische Medizin, 3-2006, S.15-17, Elsevier
  26. Muscle Energy Technique – Geschichte, Modell und Wirksamkeit Teil 1 Geschichte Osteopathische Medizin 2-2005, S.4-10, Elsevier
  27. Muscle Energy Technique – Geschichte, Modell und Wirksamkeit Teil 2 Modell Osteopathische Medizin 3-2005, S.4-10, Elsevier
  28. Muscle Energy Technique – Geschichte, Modell und Wirksamkeit Teil 3 Wirksamkeit Osteopathische Medizin 4-2005, S.4-10, Elsevier
  29. Die Behandlung der Rippen mit Muskel-Energie-Techniken Naturheilpraxis mit Naturmedizin, 10-2005, S. 1353-1359, Pflaum Verlag

Yes, I agree! The list is confusing because it contains all sorts of papers, including even interviews. Let’s do a Medline search after all and find the actual studies published by Franke:

  1. Osteopathic manipulative treatment (OMT) for lower urinary tract symptoms (LUTS) in women. Franke H, Hoesele K.J Bodyw Mov Ther. 2013 Jan;17(1):11-8. doi: 10.1016/j.jbmt.2012.05.001. Epub 2012 Jun 17.
  2. Effectiveness of osteopathic manipulative treatment for pediatric conditions: A systematic review. Franke H, Franke JD, Fryer G.J Bodyw Mov Ther. 2022 Jul;31:113-133. doi: 10.1016/j.jbmt.2022.03.013. Epub 2022 Mar 24.
  3. Muscle energy technique for non-specific low-back pain. Franke H, Fryer G, Ostelo RW, Kamper SJ. Cochrane Database Syst Rev. 2015 Feb 27;(2):CD009852. doi: 10.1002/14651858.CD009852.pub2.
  4. Osteopathic manipulative treatment for nonspecific low back pain: a systematic review and meta-analysis. Franke H, Franke JD, Fryer G.BMC Musculoskelet Disord. 2014 Aug 30;15:286. doi: 10.1186/1471-2474-15-286.
    Effectiveness of osteopathic manipulative therapy for managing symptoms of irritable bowel syndrome: a systematic review. Müller A, Franke H, Resch KL, Fryer G.J Am Osteopath Assoc. 2014 Jun;114(6):470-9. doi: 10.7556/jaoa.2014.098.
  5. Osteopathic manipulative treatment for low back and pelvic girdle pain during and after pregnancy: A systematic review and meta-analysis. Franke H, Franke JD, Belz S, Fryer G.J Bodyw Mov Ther. 2017 Oct;21(4):752-762. doi: 10.1016/j.jbmt.2017.05.014. Epub 2017 May 31.
  6. Evidence-informed management of chronic low back pain with spinal manipulation and mobilization Franke H.Forsch Komplementmed. 2008 Dec;15(6):353-4
  7. Osteopathic manipulative treatment for chronic nonspecific neck pain: A systematic review and meta-analysis Helge Franke, Jan-David Franke, Gary Fryer, 2015 Int J Osteop Med.

Not a huge list, I agree. Yet it is respectable, particularly if we consider that Franke managed to squeeze out a little positive message even from cases where the data are fairly clearly negative. Another thing that I find noteworthy is the fact that Franke, as far as I can see, never published a clinical trial. He seems to specialize in reviews – and perhaps that is understandable: if one is compelled to spinning the message from fairly negative evidence to a positive conclusion, reviews might be better suited.

Altogether, I think Helge Franke deserves his place in the ALTERNATIVE MEDICINE HALL OF FAME!

As I mentioned before: it’s the season for awards and prizes:

It goes all the way back to 1982 when the Australian Skeptics instituted an award to be presented annually at the National Convention to individuals or organisations who made the most outrageous claim of a paranormal or pseudoscientific nature in the preceding year. After conferring with leading American Skeptic and illusionist, James Randi, who had earlier instituted a Bent Spoon award, it was decided that the Australian version would also commemorate one of the less useful, though widely acclaimed, alleged paranormal claims; the psychic ability to distort items of cutlery. So was born the Australian Bent Spoon Award. Some years later, in a masterpiece of alliteration, it was decided that the preamble to the award should read “presented to the perpetrator of the most preposterous piece of paranormal or pseudoscientific piffle”.

For a nomination to be accepted it should include the following details:The Bent Spoon Award on its Plinth

  • The name and contact details of the nominator (only the name will be listed on the website)
  • The name of the person or organisation being nominated
  • The reason for the nomination, including a clear explanation of the link to the paranormal or to pseudo-science

The ‘Bent Spoon’ is reserved for people who do their woo in Australia. The organisers also reserve the right to reject nominations that are deemed inappropriate. In particular, defamatory or frivolous nominations will not be accepted.

If you feel like nominating you favourite Australian anti-hero, use this link to email your nomination for 2023.

Click here to see the list of all current nominations.

And here is the fascinating list of former winners that reads like a ‘WHO IS WHO IN AUSTRALIAN QUACKERY’:

  • 2022: Maria Carmela Pau, for selling useless COVID vaccination exemption certificates, and claiming medical qualifications she did not have.
  • 2021: Craig Kelly MP, for spreading misinformation about COVID and vaccinations, and offering dubious cures and conspiracy theories.
  • 2020: Pete Evans for the promotion of the pseudoscientific non-medical BioCharger and continuing his anti-vaccination position.
  • 2019: SBS-TV program “Medicine or Myth” for promoting certain alternative medical treatments as if they had scientific credibility as opposed to placebo effectiveness.
  • 2018: Sarah Stevenson/Sarah’s Day for the promotion of questionable natural health remedies via her vast network of followers.
  • 2017: National Institute of Complementary Medicine and the University of Western Sydney for the continued promotion of disproved and unproved alternative medicine practices.
  • 2016: Judy Wilyman, Brian Martin, and the University of Wollongong for awarding Wilyman a doctorate on the basis of a PhD thesis riddled with errors, misstatements, poor and unsupported ‘evidence’ and conspiratorial thinking.
  • 2015: Pete Evans, chef, for his diet promotions, campaigns against fluoridation and support of anti-vaccinationists.
  • 2014: Dr Larry Marshall, Chief Executive, CSIRO for his support of water divining.
  • 2013: Chiropractors’ Association of Australia and the Chiropractic Board of Australia for failing to ensure their own members – including some committee members – adhere to their policy announcements.
  • 2012: Fran Sheffield of Homeopathy Plus! for advocating the use of magical sugar and water in place of tried and true vaccination for many deadly diseases, most notably Whooping Cough.
  • 2011: RMIT University “for having a fundamentalist chiropractic education program – if the word education can be used in this way – and for endorsing the practice by targeting children and infants in their on-campus paediatric chiropractic clinics”
  • 2010: the Australian Curriculum and Reporting Authority (ACARA) for its draft science curriculum.
  • 2009: Meryl Dorey and the deceptively named Australian Vaccination Network, who spread fear and misinformation about vaccines
  • 2008: Prof Kerryn Phelps
  • 2007: Marena Manzoufas, Head of Programming at the ABC for her sterling work in authorising the television show Psychic Investigators, made worse by putting it to air in the Catalyst timeslot
  • 2006: The pharmacists of Australia, who manage to forget their scientific training long enough to sell quackery and snake oil (such as Homoeopathy and ear candles) in places where consumers should expect to get real medical supplies and advice. Video of award here.
  • 2005: The ABC television program Second Opinion for the uncritical presentation of many forms of quackery.
  • 2004: The producers of the ABC television show The New Inventors, principally for giving consideration to an obvious piece of pseudoscience, the AntiBio water water conditioning system
  • 2003: The Complementary Healthcare Council
  • 2002: Gentle Heal Pty Ltd for the selling of fake (Homoeopathic) vaccine.
  • 2001: The Lutec “Free Energy Generator”
  • 2000: Jasmuheen who claims one can live without food and water.
  • 1999: Mike Willesee for the ‘documentary’ Signs From God.
  • 1998: Southern Cross University for offering a degree course in naturopathy, while also claiming to be conducting research into whether there was actually any validity to naturopathy.
  • 1997: Dr. Viera Scheibner – Anti-immunisation advocate
  • 1996: Marlo Morgan – American new age author who claimed in her book Mutant Message Downunder, that Australian Aborigines could levitate.
  • 1995: Tim McCartney-Snape for his promotion of the Foundation for the Adulthood of Mankind.
  • 1994: Commonwealth Attorney General for an enterprise agreement with its 2,400 employees that included a clause so any employee, who had taken sick leave, need not provide a medical certificate signed by a medical practitioner, but could provide one signed by a naturopath, herbalist, iridologist, chiropractor or one of assorted other “alternative” practitioners.
  • 1993: Steve Vizard’s Tonight Live programme (Channel 7).
  • 1992: Allen S Roberts, archaeological research consultant for a search for Noah’s Ark.
  • 1991: Woman’s Day magazine for its coverage and support of the paranormal, in particular astrology.
  • 1990: Mafu, multilifed entity, channelled by Penny Torres Rubin and who, despite millennia of experience, was remarkable for the banality of his/her pronouncements.
  • 1989: Diane McCann who wrote that Adelaide was built on one of the temples of Atlantis.
  • 1988: None
  • 1987: Anne Dankbaar, Adelaide “psychic”, whose discovery of the Colossus of Rhodes created something of a media stir until it was shown to be modern builders rubble.
  • 1986: Peter Brock, prominent racing driver, whose highly touted “energy polariser” generated more heat in the motoring media than it did energy in his car.
  • 1985: The Findhorn Festival Group, which sponsored the visit to Australia of American “psychic dentist” Willard Fuller. “Brother” Willard left town just ahead of some injunctions from real dentists.
  • 1984: Melbourne Metropolitan Board of Works for its payment of $1,823 to US “psychic archaeologist” Karen Hunt to use divining rods to detect an alleged “Electromagnetic Photo Field”
  • 1983: Dennis Hassel, “medium” whose chief trick was to make his hand disappear.
  • 1982: Tom Wards, self proclaimed “psychic”, whose predictions in the popular press were renowned for their inaccuracy.

The KFF provides reliable, accurate, and non-partisan information to help inform health policy in the US. The KFF has just released its ‘Health Misinformation Tracking Poll Pilot‘ examining the public’s media use and trust in sources of health information and measuring the reach of specific false and inaccurate claims surrounding three health-related topics: COVID-19 and vaccines, reproductive health, and gun violence. It makes grimm reading indeed. Here are but a few excerpts pertaining to health/vaccination:

Health misinformation is widespread in the US with 96% of adults saying they have heard at least one of the ten items of health-related misinformation asked about in the survey. The most widespread misinformation items included in the survey were related to COVID-19 and vaccines, including that the COVID-19 vaccines have caused thousands of deaths in otherwise healthy people (65% say they have heard or read this) and that the MMR vaccines have been proven to cause autism in children (65%).

Regardless of whether they have heard or read specific items of misinformation, the survey also asked people whether they think each claim is definitely true, probably true, probably false, or definitely false. For most of the misinformation items included in the survey, between one-fifth and one-third of the public say they are “definitely” or “probably true.” The most frequently heard claims are related to COVID-19 and vaccines.

Uncertainty is high when it comes to health misinformation. While fewer than one in five adults say each of the misinformation claims examined in the survey are “definitely true,” larger shares are open to believing them, saying they are “probably true.” Many lean towards the correct answer but also express uncertainty, saying each claim is “probably false.” Fewer tend to be certain that each claim is false, with the exception of the claim that more people have died from the COVID-19 vaccines than from the virus itself, which nearly half the public (47%) recognizes as definitely false.

Across the five COVID-19 and vaccine related misinformation items, adults without a college degree are more likely than college graduates to say these claims are definitely or probably true. Notably, Black adults are at least ten percentage points more likely than White adults to believe some items of vaccine misinformation, including that the COVID-19 vaccines have caused thousands of sudden deaths in otherwise healthy people, and that the MMR vaccines have been proven to cause autism in children. Black (29%) and Hispanic (24%) adults are both more likely than White adults (17%) to say that the false claim that “more people have died from the COVID-19 vaccine than have died from the COVID-19 virus” is definitely or probably true. Those who identify as Republicans or lean towards the Republican Party and pure independents stand out as being more likely than Democratic leaning adults to say each of these items is probably or definitely true. Across community types, rural residents are more likely than their urban and suburban counterparts to say that some false claims related to COVID vaccines are probably or definitely true, including that the vaccines have been proven to cause infertility and that more people have died from the vaccine than from the virus.

Educational attainment appears to play a particularly important role when it comes to susceptibility to COVID-19 and vaccine misinformation. Six in ten adults with college degrees say none of the five false COVID-19 and vaccine claims are probably or definitely true, compared to less than four in ten adults without a degree. Concerningly, about one in five rural residents (19%), adults with a high school education or less (18%), Black adults (18%), Republicans (20%), and independents (18%) say four or five of the false COVID-19 and vaccine misinformation items included in the survey are probably or definitely true.

________________________________

If you have followed some of the comments on this blog, you might find it hard to be surprised!

I do encourage you to read the full article.

The autum seems to be the season for awards. I recently mentioned the ‘Gloden Plank‘ and now The Skeptic announced the Ockham Awards the annual awards celebrating the very best work from within the skeptical community. The awards draw attention to people who work hard to promote skepticism. The Ockhams honour outstanding campaigns, activism, blogs, podcasts, and other contributors to the skeptical cause.

Nominations for the 2023 Ockham Awards are now open! Simply complete the nomination form to submit your nominations.

A photograph of the Rusty Razor award: a rusty classic style straight razor encased in plastic with "The Rusty Razor" etched at the bottom.

The Rusty Razor is an entirely different award. It recognises individuals or organisations who have been prominent promoters of unscientific ideas within the last year. Last year’s Rusty Razor went to the Global Warming Policy Foundation, set up in 2009 by climate change denier Nigel Lawson. The Foundation has published several reports downplaying the threat of climate change.

Previous Rusty Razor winners included

  • Dr Mike Yeadon for his anti-vaccination BS,
  • Dr Didier Raoult for his promotion of hydroxychloroquine as a treatment for COVID-19,
  • Andrew Wakefield for his ongoing promotion of anti-vaxx misinformation,
  • Gwyneth Paltrow for her pseudoscience-peddling wellness empire, Goop.

The awards are, as always, based on the nominations received from the skeptical community. This is your chance to see your skeptic hero and your most prolific charlatan regognised.

So, what are you waiting for? Submit your nominations now!

Nominations will close on September 9th. Winners will be chosen by the editorial board of THE SKEPTIC, and the winners will be announced at QED in Manchester on September 23rd.

Joe Dispenza is not all that well known in Europe but, in the US,  he is all the rage as a health guru. Despite pretending to be a top (neuro)scientist and expert of quantum physics, Dispenza has, as far as I can see, just three Medline-listed papers to his credit. Here are their abstracts:

No 1 is entitled “Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease

The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. Management of the pandemic has relied mainly on SARS-CoV-2 vaccines, while alternative approaches such as meditation, shown to improve immunity, have been largely unexplored. Here, we probe the relationship between meditation and COVID-19 disease and directly test the impact of meditation on the induction of a blood environment that modulates viral infection. We found a significant inverse correlation between length of meditation practice and SARS-CoV-2 infection as well as accelerated resolution of symptomology of those infected. A meditation “dosing” effect was also observed. In cultured human lung cells, blood from experienced meditators induced factors that prevented entry of pseudotyped viruses for SARS-CoV-2 spike protein of both the wild-type Wuhan-1 virus and the Delta variant. We identified and validated SERPINA5, a serine protease inhibitor, as one possible protein factor in the blood of meditators that is necessary and sufficient for limiting pseudovirus entry into cells. In summary, we conclude that meditation can enhance resiliency to viral infection and may serve as a possible adjuvant therapy in the management of the COVID-19 pandemic.

No 2 is entitled “The Mathematical Characterization of the Complexity Matching during a Healing Circle Meditation

The aim of the study is to evaluate the complexity matching between the HRVs of the group of Healers and the Healee during the various stages of the meditation protocol by employing a novel mathematical approach based on the H-rank algorithm. The complexity matching of heart rate variability is assessed before and during a heart-focused meditation in a close non-contact healing exercise. The experiment was conducted on a group of individuals (eight Healers and one Healee) throughout the various phases of the protocol over a ~75-minute period. The HRV signal for the cohort of individuals was recorded using high resolution HRV recorders with internal clocks for time synchronization. The Hankel transform (H-rank) approach was employed to reconstruct the real-world complex time series in order to measure the algebraic complexity of the heart rate variability and to assess the complexity matching between the reconstructed H-rank of the Healers and Healee during the different phases of the protocol. The integration of the embedding attractor technique was used to aid in the visualization of reconstructed H-rank in state space across the various phases. The findings demonstrate the changes in the degree of reconstructed H-rank (between the Healers and the Healee) during the heart-focused meditation healing phase by employing mathematically anticipated and validated algorithms. It is natural and thought-provoking to contemplate the mechanisms causing the complexity of the reconstructed H-rank to come closer; it can be explicitly stated that the purpose of the study is to communicate a clear idea that the H-rank algorithm is capable of registering subtle changes in the healing process, and that there was no intention of delving deep to uncover the mechanisms involved in the HRV matching. Therefore, the latter might be a distinct goal of future research.

No 3 is entitled “Large effects of brief meditation intervention on EEG spectra in meditation novices

This study investigated the impact of a brief meditation workshop on a sample of 223 novice meditators. Participants attended a three-day workshop comprising daily guided seated meditation sessions using music without vocals that focused on various emotional states and intentions (open focus). Based on the theory of integrative consciousness, it was hypothesized that altered states of consciousness would be experienced by participants during the meditation intervention as assessed using electroencephalogram (EEG). Brainwave power bands patterns were measured throughout the meditation training workshop, producing a total of 5616 EEG scans. Changes in conscious states were analysed using pre-meditation and post-meditation session measures of delta through to gamma oscillations. Results suggested the meditation intervention had large varying effects on EEG spectra (up to 50 % increase and 24 % decrease), and the speed of change from pre-meditation to post-meditation state of the EEG co-spectra was significant (with 0.76 probability of entering end-meditation state within the first minute). There was a main 5 % decrease in delta power (95 % HDI = [-0.07, -0.03]); a global increase in theta power of 29 % (95 % HDI = [0.27, 0.33]); a global increase of 16 % (95 % HDI = [0.13, 0.19]) in alpha power; a main effect of condition, with global beta power increasing by 17 % (95 % HDI = [0.15, 0.19]); and an 11 % increase (95 % HDI = [0.08, 0.14]) in gamma power from pre-meditation to end-meditation. Findings provided preliminary support for brief meditation in altering states of consciousness in novice meditators. Future clinical examination of meditation was recommended as an intervention for mental health conditions particularly associated with hippocampal impairments.

Unimpressed?

Me too!

It seems noteworthy that none of these articles support any of the many outlandish therapeutic claims Dispenza makes. In these papers, Dispenza give his affiliation as “Encephalon, LLC, Rainier, WA”. My seraches for this institution led me to the website of Dispenza’s company that tries to sell you all sorts of strange stuff and bombards you with irritating platitudes about spirituality and related subjects. Here you will also find several of Dispenza’s books. Naturally, they were big successes. The latest volume is called ‘Becoming Supernatural‘. Its topics include:

  • Demystifying the body’s seven energy centers and how you can balance them to heal
  • How to free yourself from the past by reconditioning your body to a new mind
  • How you can create reality in the generous present moment by changing your energy
  • The difference between third-dimension creation and fifth-dimension creation
  • The secret science of the pineal gland and its role in accessing mystical realms of reality
  • The distinction between space-time vs. time-space realities

By now, I am beginning to suspect that “Dr. Joe”, as he likes to wrongly depict himself, is an 18 carrat bullshitter, and I feel like learning more about him and his incredible popularity.

So, who is Joe Dispenza?

Dispenza trained as a chiropractor and, in 1986, he had a cycling accident that left him with six compressed vertebrae – at least that is what he likes to tell journalists. Allegedly, doctors told him he might never walk again and recommended spine surgery. But he knew better, checked himself out of the hospital, and reconstructed his vertebrae with his mind. Within 10 weeks he was walking again. “I made a deal with myself that if I was ever able to walk again I would spend the rest of my life studying the mind-body connection,” he claimed in a 2018 interview. If you don’t know about vertebral compression fractures, this sounds like an unusal recovery. If you, however, know about such injuries, the course of events is not abnormal.

Ever since, Dispenza uses his mind to heal others. His website contains ~40 testimonials of people claiming he cured their cancer or their multiple sclerosis or their infertility. Under the heading of “coherence healing,” the site boasts Dispenza and his disciples have “produced profound biological changes in multitudes of individuals around the world” and “observed hundreds of healings from a wide variety of health conditions.” In a 2020 interview Dispenza bragged about bringing children onstage at his retreats to cure them of “really serious health conditions.” He claimed to have cured a 76-year-old woman of Parkinson’s. He said his treatments cured illness faster than chemotherapy and that “profound and prestigious universities” in the United States wanted to study his methods. “[We’ve seen] tumors disappearing, people stepping out of wheelchairs, blind people seeing, deaf people hearing—crazy stuff,” he stated. “This is biblical proportions stuff.”

Dispenza likes to present himself as a scientist. “Learning” becomes “forging new synaptic connections” and changing one’s behavior becomes “reorganizing circuits.” He claims that meditating in the presence of others—combining “coherent fields,” as he calls this—opens up “interference patterns of fractal geometry that are doors to dimensions.” During performances, he occasionally brings followers on stage to share the “miracles” they experienced at the workshops that day, such as a woman who claimed she regained her depth perception after decades of encephalitis. “She got a biological upgrade … and all she did was make up her mind to do it,” he told the audience.

Back in 2012, I published a post entitled “How to become a charlatan” where I provide several practical instructions for all who intend to persue this career:

1. Find an attractive therapy and give it a fantastic name

Did I just say “straight forward”? Well, the first step isn’t that easy, after all. Most of the really loony ideas turn out to be taken: ear candles, homeopathy, aura massage, energy healing, urine-therapy, chiropractic etc. As a true charlatan, you want your very own quackery. So you will have to think of a new concept.

Something truly ‘far out’ would be ideal, like claiming the ear is a map of the human body which allows you to treat all diseases by doing something odd on specific areas of the ear – oops, this territory is already occupied by the ear acupuncture brigade. How about postulating that you have super-natural powers which enable you to send ‘healing energy’ into patients’ bodies so that they can repair themselves? No good either: Reiki-healers might accuse you of plagiarism.

But you get the gist, I am sure, and will be able to invent something. When you do, give it a memorable name, the name can make or break your new venture.

2. Invent a fascinating history

Having identified your treatment and a fantastic name for it, you now need a good story to explain how it all came about. This task is not all that tough and might even turn out to be fun; you could think of something touching like you cured your moribund little sister at the age of 6 with your intervention, or you received the inspiration in your dreams from an old aunt who had just died, or perhaps you want to create some religious connection [have you ever visited Lourdes?]. There are no limits to your imagination; just make sure the story is gripping – one day, they might make a movie of it.

3. Add a dash of pseudo-science

Like it or not, but we live in an age where we cannot entirely exclude science from our considerations. At the very minimum, I recommend a little smattering of sciency terminology. As you don’t want to be found out, select something that only few experts understand; quantum physics, entanglement, chaos-theory and Nano-technology are all excellent options.

It might also look more convincing to hint at the notion that top scientists adore your concepts, or that whole teams from universities in distant places are working on the underlying mechanisms, or that the Nobel committee has recently been alerted etc. If at all possible, add a bit of high tech to your new invention; some shiny new apparatus with flashing lights and digital displays might be just the ticket. The apparatus can be otherwise empty – as long as it looks impressive, all is fine.

4. Do not forget a dose of ancient wisdom

With all this science – sorry, pseudo-science – you must not forget to remain firmly grounded in tradition. Your treatment ought to be based on ancient wisdom which you have rediscovered, modified and perfected. I recommend mentioning that some of the oldest cultures of the planet have already been aware of the main pillars on which your invention today proudly stands. Anything that is that old has stood the test of time which is to say, your treatment is both effective and safe.

5. Claim to have a panacea

To maximise your income, you want to have as many customers as possible. It would therefore be unwise to focus your endeavours on just one or two conditions. Commercially, it is much better to affirm in no uncertain terms that your treatment is a cure for everything, a panacea. Do not worry about the implausibility of such a claim. In the realm of quackery, it is perfectly acceptable, even common behaviour to be outlandish.

6. Deal with the ‘evidence-problem’ and the nasty sceptics

It is depressing, I know, but even the most exceptionally gifted charlatan is bound to attract doubters. Sceptics will sooner or later ask you for evidence; in fact, they are obsessed by it. But do not panic – this is by no means as threatening as it appears. The obvious solution is to provide testimonial after testimonial.

You need a website where satisfied customers report impressive stories how your treatment saved their lives. In case you do not know such customers, invent them; in the realm of quackery, there is a time-honoured tradition of writing your own testimonials. Nobody will be able to tell!

7. Demonstrate that you master the fine art of cheating with statistics

Some of the sceptics might not be impressed, and when they start criticising your ‘evidence’, you might need to go the extra mile. Providing statistics is a very good way of keeping them at bay, at least for a while. The general consensus amongst charlatans is that about 70% of their patients experience remarkable benefit from whatever placebo they throw at them. So, my advice is to do a little better and cite a case series of at least 5000 patients of whom 76.5 % showed significant improvements.

What? You don’t have such case series? Don’t be daft, be inventive!

8. Score points with Big Pharma

You must be aware who your (future) customers are (will be): they are affluent, had a decent education (evidently without much success), and are middle-aged, gullible and deeply alternative. Think of Prince Charles! Once you have empathised with this mind-set, it is obvious that you can profitably plug into the persecution complex which haunts these people.

An easy way of achieving this is to claim that Big Pharma has got wind of your innovation, is positively frightened of losing millions, and is thus doing all they can to supress it. Not only will this give you street cred with the lunatic fringe of society, it also provides a perfect explanation why your ground-breaking discovery has not been published it the top journals of medicine: the editors are all in the pocket of Big Pharma, of course.

9. Ask for money, much money

I have left the most important bit for the end; remember: your aim is to get rich! So, charge high fees, even extravagantly high ones. If your treatment is a product that you can sell (e.g. via the internet, to escape the regulators), sell it dearly; if it is a hands-on therapy, charge heavy consultation fees and claim exclusivity; if it is a teachable technique, start training other therapists at high fees and ask a franchise-cut of their future earnings.

Over-charging is your best chance of getting famous – or have you ever heard of a charlatan famous for being reasonably priced?  It will also get rid of the riff-raff you don’t want to see in your surgery. Poor people might be even ill! No, you don’t want them; you want the ‘worried rich and well’ who can afford to see a real doctor when things should go wrong. But most importantly, high fees will do a lot of good to your bank account.

 

Could it be that Joe Dispenza is the most successful pupil of my crash-course in charlatanism?

 

 

PS

I have been asked by the NY Post to answer a few questions about Dispenza. Allow me to present them to you here:

What makes Dispenza so dangerous (his advice, obsession with manifesting, etc.)?

Dispenza is at his most dangerous firstly when he implies that he can cure serious illness. In this way, he can cause the premature death of many patients. Secondly, he systematically undermines rational thinking which inevitably will cause significant harm to the already badly damaged US society. As Voltaire once pointed out: those who make you believe in absurdities can make you commit atrocities.

 

Why, in your opinion, has he amassed a cult-like following?

In 2012 I published a satirical piece entitled ‘How to become a charlatan’ (How to become a charlatan (edzardernst.com)). It seems to me that Dispenza followed my instructions to the letter providing a masterclass on fooling the public. He is a textbook example of a charismatic pseudoscientist (e.g.: I am a “researcher of epigenetics, quantum physics & neuroscience“) touting pure bullshit (e.g.: “new science is emerging that empowers all human beings to create the reality they choose”). He may be a charlatan but he is very good at it, runs a highly sophisticated campaign, and is laughing all the way to the bank.

 

For readers who find themselves enamored by Dispenza, what advice would you give them?

My advise is to take a step back and do a reality check: ‘Dr.Joe’ is not a medical doctor or neuroscientist but a chiropractor. He does not understand quantum physics. He has not published any meaningful scientific studies. His proclamations are nothing but platitudes or empty phrases. My advice also is to ask yourself: are you sure you are not the victim of your own gullibility?

The “Golden Plank in Front of the Head” is a satirical negative prize awarded since many years by the Vienna Sceptics. It is given to people and organisations who seek money, fame or influence with scientifically refuted theories, although they should have known better long ago. From miracle healers to divining rods – the world of esoteric nonsense is large and wide. At the “Golden Plank” award ceremony, the year’s highlights are presented and the most outstanding of them is chosen.

It is goof fun – I remember that once even Charles Windsor had been nominated – and have reported about this award before; e.g.:

An Austrian paper just reported the good news that, after the interruption due to the pandemic, the previously yearly event is happening again:

The years of the pandemic and Russia’s war of aggression against Ukraine have led to even the most nonsensical counterfactual and anti-scientific theories finding an audience. Often enough, these claims themselves came along in the white cloak of science – but in doing so, they twisted the findings of scientific studies or referred to those that were highly questionable.

The list of possible candidates is correspondingly long … some of the masterminds of the anti-vaccination and anti-pandemic movement such as the doctor Maria Hubmer-Mogg, her colleague Andreas Sönnichsen, who called the Covid vaccinations “the biggest medical scandal of all time”, and the psychiatrist Raphael Bonelli.

Political scientist Ulrike Guérot qualified as a candidate on several occasions – both with her claims during the pandemic and on the Russian war against Ukraine (“thus it becomes clear that Ukraine was given the role of starting a war with Russia on behalf of the West”).

But also former science journalists like Peter F. Mayer, who continues to twist scientific studies at will on a daily basis with his tkp blog, and Bert Ehgartner have made their sweary contributions to vaccination scepticism in Austria, which now also affects many other life-saving vaccinations. The role of some media and their representatives in the recent dissemination of anti-scientific nonsense and conspiracy ideologies, which are sometimes themselves more or less cleverly disguised as satire, should not be underestimated.

Finally, in recent months, one or the other politician – keyword: “Science is one thing, facts are another” – has manoeuvred himself into a promising position. Among the parties, the MFG, which has made anti-science part of its programme, comes to the fore. But the climate change small talkers of the ÖVP and FPÖ would also deserve a censuring mention – as well as that Austrian ruling party that has its own anti-nuclear spokesperson.

We don’t want to prejudge your favourites here, however, and look forward to receiving as many suggestions and reasons as possible. There is a separate page to officially nominate them. From all online submissions, a jury will select three finalists and finally this year’s winner. In addition, as is tradition, a “Golden Board for Lifetime Achievement” will also be awarded.

The awards ceremony will take place on 5 October 2023 in the Vienna Stadtsaal. This year, for the first time, there will also be an audience award, which will be decided live by the guests. Martin Puntigam from the Science Busters and Andre Wolf from Mimikama will host the evening. The laudations will be given by medical historian Daniela Angetter-Pfeiffer, psychiatrist and neurologist Heidi Kastner and health scientist and epidemiologist Gerald Gartlehner. According to the organisers, it will be an evening to learn, to laugh and to shake one’s head.

________________________

If you want to nominate someone of your choice (I believe they consider international charlatans as well), you can do it here: Das Goldene Brett 2023 – Der Negativpreis 🏆 (goldenesbrett.guru)

For about 40 years, the RMIT University in Australia had a Bachelor of Health Science/Bachelor of Applied Science (Chiropractic), probably the first official course of its kind in Australia. “Get qualified with a chiropractic degree: a solid grounding in anatomy, physiology and pathology and practise at the RMIT Health Clinic” was how the RMIT advertised it. But now the website states this: “from 2023, this degree is no longer offered.”

The Australian Chiropractors Association (ACA) is appalled!!!

What is more, they claim that this decision was made without consultation with staff, students (Australian or international) or other relevant stakeholders such as the chiropractic professional bodies. A publicly funded university acting in this manner appears to fly in the face of the Albanese government’s positive philosophy around educational access, particularly for those in the regions.
What the ACA omits to mention is that the chiro-unit at the RMIT has a dismal research output and hardly ever tackled relevant research questions such as effectiveness and safety of spinal manipulations. The ACA have even posted a video and believe a public institution that selectively closes a program which serves the public health interest and is economically viable, requires scrutiny. Given the role chiropractors play in serving the ageing population, together with the fact that low back pain is the number one disability worldwide, this decision is contrary to future community needs and industry demands.
Really?
The role chiros play in terms of public health, serving the elderly, alleviating back pain, reducing disability is close to zero. The fact that it is not nothing at all is due to the fact that, arguably, it is a detrimental role. As we have discussed ad nauseam on this blog:
  • the main contribution of chiros to public health is that many of them advise AGAINST immunizations;
  • a significant contribution by chiropractors to the health of the elderly is that they have put many of them in wheelchairs.
The ACA state that they believe an institution funded by government must be accountable to its stakeholders both within and without.
Exactly!
I suspect and hope that this is precisely the reason why they closed the course.
Well dome RMIT!
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