MD, PhD, MAE, FMedSci, FRSB, FRCP, FRCPEd.

The year 2024 brought many disappointments. But let’s not dwell on those, lets get in the mood for tonights celebrations! And what could be more fitting for that than a review of the positive cardiovascular effects of wine drinking? After all wine involves both aromatherapy as well as antioxidants, botanical medicine and naturopathy! As luck would have it, we even have some recent evidence on this very subject.

The objectives of this systematic review and meta-analysis were:

  • (i) to examine the association between wine consumption and cardiovascular mortality, cardiovascular disease (CVD), and coronary heart disease (CHD),
  • (ii) to analyse whether this association could be influenced by personal and study factors, including the participants’ mean age, the percentage of female subjects, follow-up time and percentage of current smokers.

The searched several databases for longitudinal studies from their inception to March 2023.

A total of 25 studies were included in the systematic review, and 22 could be included the meta-analysis. The pooled risk ration (RR) for the association of wine consumption and the risk of CHD using the DerSimonian and Laird approach was 0.76 (95% CIs: 0.69, 0.84), for the risk of CVD was 0.83 (95% CIs: 0.70, 0.98), and for the risk of cardiovascular mortality was 0.73 (95% CIs: 0.59, 0.90).

The authors concluded that their research revealed that wine consumption has an inverse relationship to cardiovascular mortality, CVD, and CHD. Age, the proportion of women in the samples, and follow-up time did not influence this association. Interpreting these findings with prudence was necessary because increasing wine intake might be harmful to individuals who are vulnerable to alcohol because of age, medication, or their pathologies.

What, you suspect that this paper was sponsored by the wine industry?

No, you are mistaken! It was funded by FEDER funds, by a grant from the University of Castilla-La Mancha, and by a grant from the science, innovation and universities.

So, maybe just for tonight we put the worries about our livers aside and enjoy a (non-homeopathic) dose of wine.

Cheers!

8 Responses to A cheerful note to end the year!

  • Cheerio!

    Happy new year!

    Drink all bottles of wine today but take a look at Parkinson like Bas Bloem had done.

    https://www.dw.com/de/vergiftetes-land-parkinson-die-bauern-und-die-g%C3%A4rtner/video-59284966

  • cv mortality is important…. but i want to see the total impact of alcohol on society.
    I hope that will be smaller in 2025!

    Cheers with a glass of water!
    Hans

  • Cheers to a study that profited, at least partly, from the Spanish wine industry.

    From Wiki (as my experiences as a tourist in C-LM don’t count):

    Castilla–La Mancha has some of the most extensive vineyards in Europe, nearly 700,000 hectares (1,700,000 acres).
    https://en.m.wikipedia.org/wiki/Castilla–La_Mancha#Agriculture_and_husbandry

    Cheers too to wine and all kinds of sparkling fluids that come without alcohol these days, or 0% beer, gin, rum.

    Thank you for being one of the scicomm trailblazers and beacons.

    To 2025. We ride at dawn.

  • I take a small glass of red, three times a week, along with my cancer diet and I am still here, 7 years later! (advanced prostate cancer) because I like it 🙂 and who knows, it might be “signalling” choice too? (see this year’s Royal Institution Christmas Lectures good for the kids and the adults!).

  • I’ll drink to that!

    Allen ein frohes neues Jahr!

  • Sorry, but I’m confused–I read the results as being negative!

    “…revealed that wine consumption has an inverse relationship to cardiovascular mortality, CVD, and CHD.”

    And

    “An inverse relationship, also known as a negative correlation, refers to a situation in which two variables move in opposite directions. When one variable increases, the other decreases, and vice versa.”

    Call me dim and correct me, but it seems to me that as alcohol consumption rises, health benefits decrease–So is the idea that one glass is okay? Maybe that’s where I went wrong? Trouble is, I always want a bit more–and a bit more. I do know when to stop, but my own investigations have led me to discover (I thought) that the “red wine is good for you” idea has largely been disproved. (?)

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