MD, PhD, MAE, FMedSci, FRSB, FRCP, FRCPEd.

herbal medicine

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“An American doctor invented a drug that claims to cure COPD within three days.” Does this announcement herald a medical sensation or a bogus and potentially dangerous falsehood?

The inventors proudly opt for the former: “we have created a revolutionary pill that combines over 60 natural herbs specifically designed to treat respiratory diseases such as chronic obstructive pulmonary disease, chronic bronchitis, and pulmonary fibrosis”

There are also videos promoting a “revolutionary pill” that allegedly cured chronic obstructive pulmonary disease (COPD) “within three days” went viral on Facebook. The videos featured public figures like Fox News anchor Jesse Watters, as well as the alleged developer of the drug, surgeon and TV personality Mehmet Oz, popularly known as “Dr. Oz”. Although the images used in the videos varied from post to post, all the videos we found used the exact same narration and promised “to pay one million dollars” if the drug failed to cure COPD. However, these videos showed clear signs of manipulation.

Altered or artificial intelligence-generated videos featuring celebrities and major TV networks have been profusely used for scams over the past few years. Science Feedback documented several examples of such doctored videos falsely promoting diabetes cures and cannabidiol (CBD) gummies as a treatment for a wide range of medical conditions. “Dr. Oz” has often been mentioned either as a developer of these products or as endorsing them, though he’s repeatedly denied any involvement in these ads. In a 2019 article for the Wall Street Journal that he also shared on Facebook and Twitter, Oz stated that these ads weren’t “legit” and warned about potential scams exploiting his image.

Likewise, the COPD videos posted on Facebook are also false. First, COPD currently has no known cure, so any product claiming to cure it is simply a scam. Second, the poor synchronization between video and audio suggests that the audio isn’t authentic.

SCIENCE FEEDBACK‘ thus conclused as follows:

Chronic obstructive pulmonary disease (COPD) is a chronic progressive lung disease for which no cure currently exists. Along with medication, lifestyle changes like quitting smoking, avoiding polluted environments, and keeping physically active can help manage the symptoms and slow down the progression of the disease. Products claiming to cure COPD are deceptive and potentially dangerous, as they may contain harmful ingredients or interact with medications in unpredictable ways.

I could not agree more and might add that – as always in suspect cases – if it sounds too good to be true, it probably is.

More reason to worry about our royal family? Apparently, Camilla (I apologise for calling her thus, as I am never entirely sure whether she is Queen or Queen Consort: Camilla, the wife of Prince Charles, will be formally known as Queen Consort now that her husband is King12When Camilla and Charles married in a civil ceremony in 2005, it was announced Camilla would become known as Princess Consort – rather than Queen Consort – due to public sensitivity3However, Queen Elizabeth II granted her the title of Queen Consort in February last year during the Platinum Jubilee45.) has been urged to take more time to recover after a bout of pneumonia.

At the start of November it was announced that she had been diagnosed with a ‘chest infection’ and was under doctors’ supervision. The 77-year-old Camilla was forced to withdraw from her engagements so she could rest at home. She has now revealed that she was suffering from a form of pneumonia.

It is understood Camilla’s condition was viral. She seems to be suffering significantly diminished reserves of energy following her chest infection. This led to her having to pull out of a number of events over recent weeks. Even though the lung infection has now cleared, she says she is still feeling tired. She has been advised by her doctors to take more time to recover. It was confirmed yesterday on the eve of the state visit that the Queen was also reducing her role at the glam state banquet later on Dec. 3 in light of her health.

So, is there anything special that might have triggered this unfortunate turn of events? To answer this question, I refer you to my post of 31 October this year:

… King Charles arrived in Bengaluru directly from Samoa, where he attended the 2024 Commonwealth Heads of Government Meeting from October 21-26. His visit to Bengaluru was strictly kept under wraps, and he was directly taken to Soukya International Holistic Health Centre (SIHHC), where he was also joined by his wife, Camilla.

According to sources, the couple’s day begins with a morning yoga session, followed by breakfast and rejuvenation treatment before lunch. After a brief rest, a second round of therapies follows, ending with a meditation session before dinner and lights out by 9 pm. They have been enjoying long walks around the campus, visiting the organic farm and cattle shed. Considering the high-profile secret visit, a high-security ring was thrown around SIHHC.

The health centre, founded by Dr. Issac Mathai, is located in Samethanahalli, Whitefield, on Bengaluru’s outskirts. This integrative medical facility combines traditional systems of medicine, including Ayurveda, Homoeopathy, Yoga, and Naturopathy, along with over 30 complementary therapies like reflexology, acupuncture, and dietetics.

… The royal couple has earlier taken wellness treatments, including anti-ageing, detoxification and rejuvenation. On November 14, 2019, the couple celebrated the then Prince Charles’ 71st birthday at SIHHC, an event that attracted a lot of publicity, unlike this visit.

Yes, you may well ask: isn’t Ayurvedic medicine supposed:

  • to strengthen the immune system,
  • to fortify you against infections,
  • to replenish your reserves of energy,
  • to enable you to recover swiftly from infections?

Of course, I know, correlation is not causation! Perhaps the recent Ayurvedic pampering in India and Camilla’s inability to make a timely recovery from what started merely as a ‘chest infection’ are not at all linked in any way. Yet, it does seem tempting to speculate that the stay in the SIHHC with all the Ayurvedic medicine did her not a lot of good.

Whatever might be the case, I would like to take this opportunity to wish Camilla a full recovery for her condition.

 

A journalist from the DAILY MAIL alerted me to the fact that yet another celebrity having decided to sell dietary supplements, interviewed me on the subject, and eventually published an article about it. One would not have thought that the Beckhams are short of money – so, why did David Beckham turn into a snake-oil salesman? I am far from being able to answer this question. What I now do know is that, via his firm ‘IM8’, he has started marketing two supplements (one of his slogans is ‘Built by Science, Trusted by Beckham’):

Daily Ultimate Essentials: All-in-One Supplement

This is a ‘multi-everything’ supplement. The only truly remarkable thing about it is its price tag. There are hundreds of similar products on the market. Almost all of them are much cheaper, and none is helpful for anyone who is healthy and consumes a balanced diet, as far as I can see.

Daily Ultimate Longevity: Healthy Aging

The implication here seems to be not a trivial one; the name clearly implies that we live longer, if we regularly bought this supplement. Not onlly that, we would also be healthier! I can see no evidence for either of these claims, yet a simple calculation tells me that we would be considerably poorer, if we fell for this advertising gimmick.

On the website, we learn a bit more:

At IM8, our commitment to science goes beyond innovation—it’s the foundation of everything we do. A world-class team of experts from space science, medicine, and academia has united with one goal: to revolutionize wellness. We’ve pioneered CRT8™ (Cell Rejuvenation Technology 8), designed to enhance cellular rejuvenation and push the limits of what’s possible in health.

Each of our products undergoes rigorous third-party testing and clinical trials, ensuring purity, efficacy, and results you can trust. With IM8, you’re getting scientifically driven core nutrition for optimal health and longevity.

___________________

I feel embarrassed for the ‘world-class team of experts from space science, medicine, and academia’ who give their good name to this hyped up nonsense. Moreover, I ask myself whether David Beckham’s new attempt to increase his wealth might be a case for the Advertising Standards Authority (ASA).

 

We all tend to believe that natural means harmless. Sadly this notion is far from true. The Korea Adverse Event Reporting System (KAERS) compiles spontaneously reported adverse event data for medicinal products including herbal medicines. This study analyzed adverse event data specifically related to herbal medicine products from the KAERS database.

Individual case safety reports (ICSRs) encompassing 84 types of herbal medicine products, identified by item codes from 2012 to 2021, were extracted from the KAERS database. Descriptive statistics were employed to analyze the characteristics of the extracted reports, and adverse event information was systematically categorized and analyzed based on the MedDRA System Organ Class and preferred term classification.

In total, 1,054 ICSRs were extracted, with some documenting multiple adverse events in a single ICSR, resulting in 1,629 extracted adverse events. When categorized by the MedDRA System Organ Class, gastrointestinal disorders were the most prevalent (28.7%), followed by skin and subcutaneous tissue disorders (20.1%). Based on the preferred terms, the most frequently reported adverse events were:

  • diarrhea (5.8%),
  • urticaria (5.3%),
  • pruritus (4.7%),
  • rash (4.4%),
  • abdominal discomfort (4.2%).

The most frequently reported herbal medicines were:

  • Bangpungtongseong-san (297 cases),
  • Kyeongok-go (144 cases),
  • Eunkyo-san (108 cases).

The authors conclused that spontaneously reported adverse events associated with herbal medicine products were systematically documented using the KAERS database. This study, which focused on voluntarily reported adverse reactions, underscores the need for additional research to estimate the incidence rate of adverse events and assess causality.

The authors also noted that serious adverse events, including death, life-threatening conditions, initial or prolonged hospitalization, and other importantmedical events, were individually evaluated for each reported adverse event. Out of the 1,054 ICSRs, 48 (4.6%) included one or more serious adverse events (four ICSRs were identified with duplicate labels spanning two serious adverse event categories). Further, among the 1,629 adverse events, 99 (6.1%) were identified as serious adverse events. Two cases of death were reported, with causality categorized as unknown or unlikely. Regarding life-threatening conditions, three cases of dyspnea, nausea, and dizziness have been reported, all of which resulted in recovery. Thirty-one cases of initial or prolonged hospitalization have been reported. Among the adverse events associated with hospitalization (51 events in total, considering the multiple events reported in one ICSR with hospitalization), the most frequent were:

  • increased aspartate amino transferase and alanineaminotransferase levels (7 case seach),
  • dyspnea (3 cases),
  • liver function test abnormality (2 cases),
  • nausea (2 cases),
  • rash (2 cases).

Sixteen cases of other important medical events were reported, and among 43 related events, dyspnea (5 cases), angioedema (4 cases), urticaria (4 cases), anaphylactic reaction (3 cases), chest discomfort (2 cases), and dizziness (2 cases) were reported.

Yes, the ‘natural equals harmless’ fallacy is very widespread. It certainly is an excellent advertising gimmick. However, as this study demonstrates very clearly, it is as fallacious as it is dangerous.

It has been reported that King Charles is on a secret trip to Bengaluru, his first visit to India since being coronated as king of the United Kingdom on May 6, 2023, at Westminster Abbey, London. Charles arrived in Bengaluru on October 27 and will be at the Soukya International Holistic Health Centre (SIHHC) in Whitefield for wellness treatment till Wednesday (30/10) night, when he is expected to fly to London.

Sources privy to his secret visit said that King Charles arrived in Bengaluru directly from Samoa, where he attended the 2024 Commonwealth Heads of Government Meeting from October 21-26. His visit to Bengaluru was strictly kept under wraps, and he was directly taken to SIHHC, where he was also joined by his wife, Queen Camilla.

According to sources, the couple’s day begins with a morning yoga session, followed by breakfast and rejuvenation treatment before lunch. After a brief rest, a second round of therapies follows, ending with a meditation session before dinner and lights out by 9 pm. They have been enjoying long walks around the campus, visiting the organic farm and cattle shed. Considering the high-profile secret visit, a high-security ring was thrown around SIHHC.

The health centre, founded by Dr. Issac Mathai, is located in Samethanahalli, Whitefield, on Bengaluru’s outskirts. This integrative medical facility combines traditional systems of medicine, including Ayurveda, Homoeopathy, Yoga, and Naturopathy, along with over 30 complementary therapies like reflexology, acupuncture, and dietetics.

Although this is his first visit as a monarch, Charles has visited the centre on nine earlier occasions and celebrated Deepavali on three occasions there. The royal couple has earlier taken wellness treatments, including anti-ageing, detoxification and rejuvenation. On November 14, 2019, the couple celebrated the then Prince Charles’ 71st birthday at SIHHC, an event that attracted a lot of publicity, unlike this visit.

_______________________

The website of the SIHHC modestly claims to be “THE WORLD’S FIRST INTEGRATIVE HEALTH DESTINATION’

As I reported in 2022, at a press conference in Goa it was claimed, that Prince Charles had been cured of COVID-19 after seeking treatment from a Bengaluru-based alternative treatment resort, SOUKYA International Holistic Health Centre’ run by a doctor Isaac Mathai. The Palace later denied that this was true.

And what about Dr. Issac Mathai? This is what he writes about himself:

A journey that began from the hills of Wayanad (northern Kerala) in 1985, started to bloom in 1998, and today is an international destination for Holistic health and wellbeing. When Dr. Issac Mathai embarked on this journey influenced by his mother, a Homeopathy practitioner who “helped people get better”, little did he know that one day he would lead a team to redefine the essence of health and wellbeing.

As a confident youngster aspiring to be an ‘exceptional Homeopathic Doctor’, Dr. Mathai encountered two key turning points in life – one, an internationally well-received research paper on integrating Yoga with Homeopathy to cure respiratory disorders, and two, learning at the Hahnemann Postgraduate Institute of Homeopathy, London.

Later he was made a Consultant Physician at the Hale Clinic in London, where he treated a number of high-profile people. This helped him establish a reputation in the holistic healing community in quick time. SOUKYA, is today, a residential holistic centre comparable to any facility in the world.

In a world that is comfortable with the conventional practice of ‘popping pills’, the world at large practices a combination of self-medication based on preconceived notions about what is wrong with individuals. In such a scenario, Dr. Issac Mathai and his team of experienced practitioners from different streams have achieved an important goal – create awareness about the possibility of prevention of adverse health conditions, rather than just addressing the symptom.

Education:

M.D. (Homeopathy),
Hahnemann Post-Graduate Institute of Homeopathy, London M.R.C.H, London
Chinese Pulse Diagnosis and Acupuncture, WHO Institute of Traditional Chinese Medicine, Nanjing, China
Trained (Mind-Body Medicine Programme) at Harvard Medical School, USA

Of the 3 institutions mentioned above, I could only find the last one: Harvard CME | Mind Body Medicine.

And under MD (Homeopathy), I found this: MD in Homoeopathy is a 3-year long postgraduate course in medicine including a year of house job, and remaining 2 years of research and study.

So, should we be concerned about the health of our King?

What do you think?

Mistletoe is a popular so-called alternative medicine (SCAM) often advocated for cancer. It has featured regualarly on this blog:

Now concerns about the safety of mistletoe therapy have re-surfaced.

One man was diagnosed with a neuroendocrine neoplasia of the terminal ileum that had metastasised diffusely to the liver. The patient also developed symptoms of carcinoid syndrome (flushing, sporadic diarrhoea and bronchospasticity). Somatostatin analogue therapy was started after surgical treatment in 11/2020.

The patient had independently started mistletoe injection therapy. After six weeks, he complained of several localised reactions at the injection sites, each with a very itchy ‘hazelnut-sized’ hardening. He was then advised to halve the mistletoe dose and continue the therapy. However, the local findings did not improv; the physician therefore prescribed a further dose reduction.

As a result, the local findings improved, the patient increased the dose. 30 minutes after the injection of the high dose, he felt an increasing feeling of warmth, tingling, nausea and discomfort, as well as shortness of breath and an urge to defecate. When he went to the toilet, he also experienced visual disturbances and dizziness, and eventually fell unconscious. The emergency doctor called by his wife admitted him to the nearest hospital with the diagnosis of anaphylactic shock. After inpatient diagnostics – with exclusion of a cardiopulmonary event – and successful treatment, the patient was able to leave the hospital on the second day.

Mistletoe therapy has become more popular as a supportive cancer therapy. Therefore, rare but serious to life-threatening side effects should be known to the therapists and patients, the doctors of the patient stress. The most common adverse events of mistletoe therapy are skin reactions at the injection site (pruritus, urticaria, redness ø ≤ 5 cm). One review noted that the rate of serious adverse events from mistletoe therapy was < 1 per cent. According to the above-mentioned guideline, the following are very rare side effects:

  • hypersensitivity and anaphylactic reactions,
  • intensification of autoimmune reactions,
  • local lymphoma infiltrate at the injection site.

 

The aim of this study was to investigate the prevalence and type of so-called alternative medicine (SCAM) use as well as potential factors related to SCAM use in a representative sample of US adults with self-reported post-COVID-19. This secondary data analysis was based on data from the 2022 National Health Interview Survey 2022 (NHIS) regarding presence of post-COVID-19 symptoms and CM use in a representative adult sample (weighted n = 89,437,918).
Our estimates indicate that 19.7% of those who reported having a symptomatic SARS-CoV-2 infection experienced post-COVID-19 symptoms and 46.2% of those reported using any type of SCAM in the last 12 months. Specifically, post-COVID-19 respondents used most often:
  • mind-body medicine (32.0%),
  • massage (16.1%),
  • chiropractic (14.4%),
  • acupuncture (3.4%),
  • naturopathy (2.2%),
  • art and/or music therapy (2.1%).

Reporting post-COVID-19 was associated with an increased likelihood of using any SCAM in the last 12 months (AOR = 1.18, 95% CI [1.03, 1.34], p = 0.014) and specifically to visit an art and/or music therapist (AOR = 2.56, 95% CI [1.58, 4.41], p < 0.001). The overall use of any SCAM was more likely among post-COVID-19 respondents under 65 years old, females, those with an ethnical background other than Hispanic, African-American, Asian or Non-Hispanic Whites, having a higher educational level, living in large metropolitan areas and having a private health insurance.

The authors concluded that their findings show a high prevalence of SCAM use among post-COVID-19 respondents which highlights the need for further investigations on effectiveness, safety and possible mechanisms of action.
SCAM-use tends to be particularly high for conditions that conventional medicine cannot cure. Thus it is hardly surprising that post-COVID-19 patients employ it frequently. The question is – as the authors rightly stress – which post-COVID-19 symptoms responds best to which treatment? The range of symptoms of post-COVID-19 is wide, and the range of therapeutic options to alleviate them is even wider. What we need is a series of well-designed comparative studies testing both the most so-called alternative as well as the many conventional options.

Advocates of so-called alternative medicine (SCAM) almost uniformly stress the importance of prevention and pride themselves to make much use of SCAM for the purpose of prevention. SCAM, they often claim, is effective for prevention, while conventional medicine tends to neglect it. Therefore, it seems timely to ponder a bit about the subject.

It makes sense to differentiate three types of prevention:

  1. Primary prevention aims to prevent disease or injury before it ever occurs.
  2. Secondary prevention aims to reduce the impact of a disease or injury that has already occurred.
  3. Tertiary prevention aims to soften the impact of an ongoing illness or injury that has lasting effects.

Here I will includes all three and I will ask what SCAM has to offer in any form of prevention. I will do this by looking at what we have previously discussed on this blog in relation to several specific SCAM and add in each case a very brief evaluation of the evidence.

Acupuncture

Chiropractic

Herbal medicine

Homeopathy

Mind-body therapies

Osteopathy

Does Osteopathy Prevent Motion Sickness? – NO CONVINCING EVIDENCE

Supplements

Yoga

I hope you agree: this list is impressive!

  • Impressive in the way of showing how often we have discussed SCAM for prevention in one form or another.
  • Impressive also to see how little positive evidence there is for effective prevention with SCAM

Of course, this is merely based on posts that were published on my blog. Some will argue that I missed out on some effective SCAMs for prevention. Others might claim that I judged some of the the above cited articles too harshly. If you share such sentiments, I invite you to show me the evidence – and I promise to look at it and evaluate it critically.

Meanwhile, I will draw the following conclusion:

Despite the prominent place prevention assumes in discussions about SCAM, the actual evidence fails to show that it has an important role to play in primary, secondary or tertiary prevention.

 

Having recently come across the strange and scary story of the Nazi’s experiments on Caladium Seguinum, I did some research to find out about the current medicinal uses of this plant. Perhaps unsurprisingly, it is today mostly advocated as a homeopathic remedy. In particular, it is highly recommended for erectile dysfunction (ED) and premature ejaculation. Here are some extracts from a particularly ‘impressive’ article on this topic:

… [Caladium Seguinum] … is particularly suited for treating premature ejaculation and erectile dysfunction, since these two problems cause widespread testicular swelling. The genital swelling is often associated with pruritus and internal inflammation that can be effectively treated with caladium.

The use of Caladium Seguinum is more common among men who are diagnosed with typical symptoms, along with an established case of either premature ejaculation or erectile dysfunction. Prescription of caladium is more common among men who suffer from genitals lacking vitality, wherein the penis doesn’t enter a state of arousal in a normal manner.

It has been noted that emotional and stress-linked problems are often the cause of underlying, undiagnosable causes of sexual problems among men. Similarly, ED and premature ejaculation are more commonly associated with men who are mentally exhausted or suffering from a mental trauma. In such cases, the use of caladium is applicable.

In cases wherein male impotency is linked to lifestyle habits like smoking, caladium is often prescribed. Further, premature ejaculation and erectile dysfunction in men who also complain of motion sickness are more likely to be treated with caladium. Caladium is very helpful if the premature ejaculation or erectile dysfunction has resulted in visible inflammation of the penile region, particularly redness of the glans.

Men who are suffering from ED along with symptoms like cold sweats and thickening of the scrotum skin are ideal candidates for caladium treatment. Men presenting disturbed respiratory functions, often described as an asthma-like condition, along with having erectile dysfunction are better candidates for caladium treatment.

Some of the other symptoms that contribute towards premature ejaculation and erectile dysfunction and are usually treated with caladium or caladium-enriched homeopathic mixtures include:

  • Propensity towards unintentional penile erection
  • Painful erection
  • Testicular discomfort associated with gonorrhea
  • Itching or surface eruptions on scrotal sac
  • Disturbed sleep patterns
  • Nighttime discharge from penis

Advantages of Caladium Seguinum

The biggest advantage of using homeopathic remedies for male infertility problems like erectile dysfunction is their overall safety. None of the homeopathic medications, including caladium, are known to induce any serious side-effects. However, the use of Caladium without medical supervision of a homeopathic specialist is highly inadvisable. Caladium Seguinum is retailed in various potencies and gauging the required potency is rather difficult.

For instance, Caladium Seguinum is commonly retailed with potency grading between 6X and 30X. Here, determining the appropriate potency largely depends upon understanding the associated symptoms and past medical history. In some cases, Caladium of lower potency is better suited since it is prescribed in combination with other homeopathic medications for better results.

__________________________

I think I know the question you were about to ask:

IS THERE ANY EVIDENCE FOR THESE CLAIMS?

The short answer is NO!

  • The article itself does not provide any.
  • My Medline search did not identify any.
  • Further searches were equally unsuccessful.

In fact, there is no homeopathic remedy that has been shown to be effective for the named conditions.

What is more, there is no homeopathic remedy that has been shown to be effective for ANY condition.

This begs the question as to what we should call the many claims to the contrary:

  • Wishful thinking?
  • Naive mistakes?
  • Commercials?
  • Fraud?

You decide.

 

Soon after taking power in 1933, the Nazis introduced a program of involuntary sterilisation of those German citizens who they considered unworthy of reproduction. These were predominantly, but not exclusively, people afflicted with heridetary diseases. The declared aim was to sanitize the German gene pool. Involuntary sterilisation was legalized through the ‘law for the prevention of genetically diseased offspring’ (Gesetz zur Verhuetung erbkranken Nachwuchs) as early as July 14, 1933. The law provided that handicapped individuals were to be identified, examined by a jury of experts who had to write an experts’ report, and subsequently sterilized.

In order to implement the law, a large number of new health authorities had to be established. By 1935, approximately 220 hereditary health courts and 30 higher hereditary health courts had thus been set up. Each court relied on the expertise of two physicians and one district judge. Throughout Germany, doctors were required to register with these courts every known case of hereditary illness. This included patients suffering from genetic blindness and deafness, manic depression, schizophrenia, epilepsy, congenital feeble-mindedness, Huntington’s chorea, and alcoholism. The doctors who carried out the sterilisations were paid 10 Reichsmark per case for their services.

The most common methods of sterilization were vasectomy for men and ligation of ovarian tubes for women. Around 6 000 patients, mostly women, died as a result of these operations. Because such methods sterilisations required a lengthy post-operative recovery time, the Nazis started looking for more economical methods of sterilisation. New options were thus tested on camp prisoners at Auschwitz and at Ravensbrück. For instance, experimental drugs were tried, carbon dioxide was injected and X-rays were administered. Another option that was considered was herbal medicine.

In October 1941, Adolf Pokorny, an Austrian dermatologist, wrote to Himmler. ‘Driven by the idea that the enemy must not only be defeated, but destroyed’, he suggested carrying out sterilisation experiments with the South American plant Caladium seguinum. Pokorny drew Himmler’s attention to a publication by Madaus, which suggested that the sap of the hogweed caused permanent sterility in animals:

‘If it were possible … to produce a drug that produces undetected sterilisation in humans in a relatively short time, we would have an effective weapon at our disposal. The very idea that the three million Bolsheviks currently in German captivity could be sterilised so that they would be available as workers, but excluded from reproduction, opens up far-reaching prospects.’

In order not to jeopardise the research in this regard, Pokorny recommended that plant cultivation be started soon and that Madaus be prohibited from publishing further papers on this subject so that the ‘enemy’ would not be made aware of these plans. Himmler who was easily impressed by quacks of all types instructed Oswald Pohl and Ernst-Robert Grawitz to follow up Pokorny’s tips and contact Madaus so that he could check ‘the possibility of experiments on criminals who would have to be sterilised in and of themselves’.

In the spring of 1942, the SS contacted the Madaus company. Gerhard Madaus, the company’s boss, had died shortly beforehand and his successor pledged to maintain secrecy about the effects of the plant. A chemist from IG Farben asserted that sterilisation might be possible. In October 1942, the SS placed an order for extracts to be used in human experiments. Ultimately, however, no such trials took place. There were several reasons for this:

  • the plant did not thrive in the European climate,
  • the Madaus company did not have enough glasshouses for growing the plant,
  • attempts to synthesise the plant’s ingredients failed.

After the war, Himmler committed suicide, Oswald was sentenced to death and executed, Grawitz killed himself and his family, and Pokorny was put on trial in the famous ‘Nuremberg Doctors Tribunal‘. He defended himself by arguing that he had all along been aware of the ineffectiveness of Caladium seguinum and that he had wanted to dissuade Himmler from using tried and tested methods of sterilisation with his proposal. The court did not accept his argument, but nevertheless acquitted him:

‘We are not impressed by the defence which the accused has put forward, and it is difficult to believe that he was guided by the noble motives which he states when he wrote the letter. Rather, we are inclined to believe that Pokorny wrote the letter for entirely different and more personal reasons. […] In Pokorny’s case, the prosecution has not succeeded in proving his guilt. As outrageous and base as the suggestions in this letter are, there is not the slightest evidence that any steps were ever taken to apply them through human experimentation. We therefore declare that the accused must be acquitted, not because of, but in spite of the defence he has put forward.’

Porkorny was thus released from prison; his fate thereafter is not known.

 

 

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