MD, PhD, MAE, FMedSci, FRSB, FRCP, FRCPEd.

Spanish colleagues and I just published an article entitled “Is Osteopathic Manipulative Treatment Clinically Superior to Sham or Placebo for Patients with Neck or Low-Back Pain? A Systematic Review with Meta-Analysis”. Here is its abstract:

The aim of this systematic review and meta-analysis was to compare whether osteopathic manipulative treatment (OMT) for somatic dysfunctions was more effective than sham or placebo interventions in improving pain intensity, disability, and quality of life for patients with neck pain (NP) or low-back pain (LBP). Methods: A systematic review and meta-analysis was carried out. Searches were conducted in PubMed, Physiotherapy Evidence Database, Cochrane Library, and Web of Science from inception to September 2024. Studies applying a pragmatic intervention based on the diagnosis of somatic dysfunctions in patients with NP or LBP were included. The methodological quality was assessed with the PEDro scale. The quantitative synthesis was performed using random-effect meta-analysis calculating the standardized mean difference (SMD) with RevMan 5.4. The certainty of evidence was evaluated using GRADEPro. Results: Nine studies were included in the qualitative synthesis, and most of them showed no superior effect of OMTs compared to sham or placebo in any clinical outcome. The quantitative synthesis reported no statistically significant differences for pain intensity (SMD = −0.15; −0.38, 0.08; seven studies; 1173 patients) or disability (SMD = −0.09; −0.25, 0.08; six studies; 1153 patients). The certainty of evidence was downgraded to moderate, low, or very low. Conclusions: The findings of this study reveal that OMT is not superior to sham or placebo for improving pain, disability, and quality of life in patients with NP or LBP.

As always, it seems important to stress that our review has several limitations. Firstly, the searches were conducted in the most relevant databases; however, some studies not indexed in these sources may have been missed. Secondly, the diverse NP and LBP diagnosis, as well as the lack of data reported by some studies, complicates the interpretation of the results and may weaken our conclusion. Thirdly, the primary studies pragmatically applied interventions based on diagnoses of various somatic dysfunctions, resulting in a high degree of heterogeneity among the treatments applied.

Despite these limitations, it is fair to say, I think, that OMT is not nearlly as solidly supported by reliable evidence as most osteopaths try to make us believe. In essence, this means that, if you suffer from NP or LBP, you best concult a proper doctor or physiotherapist.

4 Responses to Are Osteopathic Manipulations Superior to Sham or Placebo for Neck-Pain or Low-Back Pain?

  • ” if you suffer from NP or LBP, you best concult a proper doctor or a physiotherapist”… Do you have any evidance to support this claim?

  • I was formerly trained as an osteopath (a contested term, to say the least) between 1979 and 1983, and practiced as such until 2010.

    Many of the patients who consulted me back then had already seen a “proper doctor” or a physiotherapist for neck pain and low back pain without success. However, they often recovered following a course of manual therapy, provided there were no suspicious red flags that would contraindicate its use.

    What am I to make of my anecdotal success?

    It is nearly impossible for physical therapists to distinguish between the specific effects of the intervention and the nonspecific effects that are part of the patient-practitioner relationship.

    Regards

    Paul

    • “It is nearly impossible for physical therapists to distinguish between the specific effects of the intervention and the nonspecific effects that are part of the patient-practitioner relationship.”
      very true!

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