Papillomas of dogs are benign growths caused by the canine papillomavirus. The oral mucosa and commissures of the lip are most frequently involved. Papillomas often regress spontaneously within a few weeks, and treatment is usually not necessary.
This Indian study tested the combination of 4 homeopathic drugs (Sulfur 30C, Thuja 30C, Graphites 30C, and Psorinum 30C) in 16 dogs affected with oral papillomatosis which was not undergone any previous treatment. Dogs affected with oral papillomatosis, which have not undergone any initial treatment and fed with a regular diet. They were randomly divided into two groups, namely, homeopathic treatment group (n=8) and placebo control group (n=8). The homeopathic combination and placebo (distilled water) was administered orally twice daily for 15 days. Clinical evaluation in both groups of dogs was performed by the same investigator during 12 months. Dogs were clinically scored for oral lesions on days 0, 5, 7, 10, 15, 20, 25, 30, 45, 60, 90, 120, and 150 after initiation of treatment.
The homeopathic treatment group showed early recovery with a significant reduction in oral lesions reflected by clinical score (p<0.001) in comparison to placebo-treated group. Oral papillomatous lesions regressed in the homeopathic group between 7 and 15 days, whereas regression of papilloma in the placebo group occurred between 90 and 150 days. The homeopathic treated group was observed for 12 months post-treatment period and no recurrence of oral papilloma was observed.
The authors concluded that the current study proves that the combination of homeopathy drugs aids in fastening the regression of canine oral papilloma and proved to be safe and cost-effective.
This could well become the worst SCAM study of 2020. In case you have not already spotted its flaws, here are some of them:
- the trial was truly tiny; thus the results could easily be false-positive;
- to make any conclusion about safety after treating 16 subjects is nonsensical;
- cost-effectiveness was not assessed and therefore conclusions about it are not warranted; if, however, one made a ‘back of the envelope’ calculation, one would be hard-pressed to not find tap water more cost-effective than 4 homeopathic remedies;
- the graph looks to me very suspect – could it be that someone has been busy prettifying the data?
Nevertheless, I think this paper is remarkable, if only in the way it teaches us how NOT to formulate conclusions of a study. Even if we had 200 dogs in this trial, its findings would not PROVE the efficacy of the intervention. Proof is something a single trial will never deliver. Proof is a debatable concept even after several independent replications, particularly when dealing with something as implausible as homeopathy.
In any case, if your dog has papillomas, do me a favour and avoid homeopathic vets!